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Mafenide

Also known as: 4-(Aminomethyl)benzenesulfonamide, Homosulfanilamide, Sulfamylon, alpha-Aminotoluene-4-sulphonamide, Maphenide, alpha-Amino-p-toluenesulfonamide, Homonal, Homosulfamine, Emilene, Benzamsulfonamide

Mafenide (CAS 138-39-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C7H10N2O2S and a molecular weight of 186.232 g/mol. Key properties include a melting point of 177-178℃ (decomposition), a boiling point of 382.0±44.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 184.8±28.4 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
138-39-6
Jingsj CID
J-22511-1
Molecular Formula
C7H10N2O2S
Molecular Weight
186.232 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point177-178℃ (decomposition)
Boiling Point382.0±44.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point184.8±28.4 °C
Exact Mass186.046295
PSA94.56000
LogP-0.80
Vapor Pressure0.0±0.9 mmHg at 25°C
Refractive Index1.602
Storage Conditions2-8℃

Activity & Biological Data

Additional Information[1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9.

Customs & Trade Information

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Mafenide?

The CAS number of Mafenide is 138-39-6.

What are the molecular formula and molecular weight of Mafenide?

Mafenide has molecular formula C7H10N2O2S and molecular weight 186.232 g/mol.

What are the upstream and downstream products of Mafenide?

For Mafenide, Upstream Products: 4-Cyanobenzenesulfonamide, N-[4-(Aminosulfonyl)benzyl]acetamide, 4-(Acetamidomethyl)benzenesulfonyl chloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Mafenide (CAS 138-39-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-22511-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.