Cefotaxime

Also known as: Cefotaxima acid, Cefabol, Cephotaxime, (6R,7R)-3-[(Acetyl-oxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-, HR-756, HR756, HR 756

Cefotaxime (CAS 63527-52-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C16H17N5O7S2 and a molecular weight of 455.466 g/mol. Key properties include a melting point of 162-163℃ and a density of 1.8±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 63527-52-6
Jingsj CID: J-2193-5
Molecular Formula: C₁₆H₁₇N₅O₇S₂
Molecular Weight: 455.466 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	162-163℃
Density	1.8±0.1 g/cm3
Exact Mass	455.056946
PSA	227.05000
LogP	1.20
Refractive Index	1.779
Storage Conditions	2-8℃

Activity & Biological Data

Additional Information	[1]. Hee-Chang Jang, et al. In vivo efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus sepsis. PLoS One. 2014 Jun 30;9(6):e101118. [2]. Woodfield JC, et al. A comparison of the prophylactic efficacy of ceftriaxone and cefotaxime in abdominal surgery. Am J Surg. 2003 Jan;185(1):45-9. [3]. Scholz H, et al. Prospective comparison of ceftriaxone and cefotaxime for the short-term treatment of bacterial meningitis in children. Chemotherapy. 1998 Mar-Apr;44(2):142-7. [4]. Gums JG, et al. Differences between ceftriaxone and cefotaxime: microbiological inconsistencies. Ann Pharmacother. 2008 Jan;42(1):71-9.

Additional Information

[1]. Hee-Chang Jang, et al. In vivo efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus sepsis. PLoS One. 2014 Jun 30;9(6):e101118. [2]. Woodfield JC, et al. A comparison of the prophylactic efficacy of ceftriaxone and cefotaxime in abdominal surgery. Am J Surg. 2003 Jan;185(1):45-9. [3]. Scholz H, et al. Prospective comparison of ceftriaxone and cefotaxime for the short-term treatment of bacterial meningitis in children. Chemotherapy. 1998 Mar-Apr;44(2):142-7. [4]. Gums JG, et al. Differences between ceftriaxone and cefotaxime: microbiological inconsistencies. Ann Pharmacother. 2008 Jan;42(1):71-9.

Customs & Trade Information

HS Code	3003201100

Frequently Asked Questions

What is the CAS number of Cefotaxime?

The CAS number of Cefotaxime is 63527-52-6.

What are the molecular formula and molecular weight of Cefotaxime?

Cefotaxime has molecular formula C16H17N5O7S2 and molecular weight 455.466 g/mol.

What are the upstream and downstream products of Cefotaxime?

For Cefotaxime, Upstream Products: S-2-Benzothiazolyl 2-amino-alpha-(methoxyimino)-4-thiazolethiolacetate, 7-Aminocephalosporanic acid, (Z)-4-Chloro-2-(methoxyimino)-3-oxobutanoic acid; Downstream Products: Ceftiofur, Cefpodoxime Proxetil, Cefpirome.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Cefotaxime (CAS 63527-52-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2193-5 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.