(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Also known as: H-D-Tic-OH, D-Tic, (R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid, D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, (3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, 1,2,3,4-D-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID, MFCD00144038
(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (CAS 103733-65-9) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C10H11NO2 and a molecular weight of 177.200 g/mol. Key properties include a boiling point of 372.0±42.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 178.8±27.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 103733-65-9
- Jingsj CID
- J-21730-1
- Molecular Formula
- C10H11NO2
- Molecular Weight
- 177.200 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 372.0±42.0 °C at 760 mmHg |
|---|---|
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 178.8±27.9 °C |
| Exact Mass | 177.078979 |
| PSA | 49.33000 |
| LogP | 0.86 |
| Vapor Pressure | 0.0±0.9 mmHg at 25°C |
| Refractive Index | 1.577 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Valle G, et al. Constrained phenylalanine analogues. Preferred conformation of the 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) residue. Int J Pept Protein Res. 1992 Sep-Oct;40(3-4):222-32. |
|---|
Customs & Trade Information
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid?
The CAS number of (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is 103733-65-9.
What are the molecular formula and molecular weight of (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid?
(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid has molecular formula C10H11NO2 and molecular weight 177.200 g/mol.
Is (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid hazardous?
(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid?
For (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, Upstream Products: Formaldehyde, D-Phenylalanine, Benzyl (3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate; Downstream Products: Benzyl (3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate, (R)-methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (CAS 103733-65-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-21730-1 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.