Fludrocortisone

Also known as: 9α-Fluorocortisol, 9α-Fluoro-17-hydroxycorticosterone, 9α-Fluorohydrocortisone, 9-Fluorocortisol, Fluohydrisone, Fludrocortone, Florinef, Alflorone, Astonin-H, Fluorocortisone, Fluohydrocortisone

Fludrocortisone (CAS 127-31-1) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C21H29FO5 and a molecular weight of 380.450 g/mol. Key properties include a melting point of 208-212ºC, a boiling point of 564.7±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 295.3±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 127-31-1
Jingsj CID: J-21584-9
Molecular Formula: C₂₁H₂₉FO₅
Molecular Weight: 380.450 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	208-212ºC
Boiling Point	564.7±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	295.3±30.1 °C
Exact Mass	380.199890
PSA	94.83000
LogP	1.23
Vapor Pressure	0.0±3.5 mmHg at 25°C
Refractive Index	1.584
Storage Conditions	Refrigerator

Activity & Biological Data

Additional Information	[1]. Jaal J, et al. Small Cell Lung Cancer Patient with Profound Hyponatremia and Acute Neurological Symptoms: An Effective Treatment with Fludrocortisone. Case Rep Oncol Med. 2015;2015:286029. [2]. Mori T, et al. Improved efficiency of hypervolemic therapy with inhibition of natriuresis by fludrocortisone in patients with aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery [1999, 91(6):947-952]

Additional Information

[1]. Jaal J, et al. Small Cell Lung Cancer Patient with Profound Hyponatremia and Acute Neurological Symptoms: An Effective Treatment with Fludrocortisone. Case Rep Oncol Med. 2015;2015:286029. [2]. Mori T, et al. Improved efficiency of hypervolemic therapy with inhibition of natriuresis by fludrocortisone in patients with aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery [1999, 91(6):947-952]

Customs & Trade Information

HS Code	2937210000

Frequently Asked Questions

What is the CAS number of Fludrocortisone?

The CAS number of Fludrocortisone is 127-31-1.

What are the molecular formula and molecular weight of Fludrocortisone?

Fludrocortisone has molecular formula C21H29FO5 and molecular weight 380.450 g/mol.

What are the upstream and downstream products of Fludrocortisone?

For Fludrocortisone, Upstream Products: Fludrocortisone acetate, 11-Epihydrocortisone, Anecortave Acetate; Downstream Products: Isoflupredone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Fludrocortisone (CAS 127-31-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-21584-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.