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2',5'-Dihydroxyacetophenone

Also known as: 2,5-Dihydroxyacetophenone, 2-Acetylhydroquinone, Quinacetophenone, 1-(2,5-Dihydroxyphenyl)ethanone, Acetylhydroquinone, 2',5'-Dihydroxyacetophenone

2',5'-Dihydroxyacetophenone (CAS 490-78-8) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H8O3 and a molecular weight of 152.147 g/mol. Key properties include a melting point of 204-206 °C(lit.), a boiling point of 329.2±27.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 167.1±20.2 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
490-78-8
Jingsj CID
J-21445-9
Molecular Formula
C8H8O3
Molecular Weight
152.147 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point204-206 °C(lit.)
Boiling Point329.2±27.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point167.1±20.2 °C
Exact Mass152.047348
PSA57.53000
LogP1.59
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.595
Additional Propertyinsoluble

Activity & Biological Data

TargetERK1 ERK2 NF-κB
Additional Information[1]. Han Y, et al. 2,5-dihydroxyacetophenone isolated from Rehmanniae Radix Preparata inhibits inflammatoryresponses in lipopolysaccharide-stimulated RAW264.7 macrophages. J Med Food. 2012 Jun;15(6):505-10.

Customs & Trade Information

HS Code2914501900
Summary2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 2',5'-Dihydroxyacetophenone?

The CAS number of 2',5'-Dihydroxyacetophenone is 490-78-8.

What are the molecular formula and molecular weight of 2',5'-Dihydroxyacetophenone?

2',5'-Dihydroxyacetophenone has molecular formula C8H8O3 and molecular weight 152.147 g/mol.

What are the upstream and downstream products of 2',5'-Dihydroxyacetophenone?

For 2',5'-Dihydroxyacetophenone, Upstream Products: 1,4-Diacetoxybenzene, 1-(2,5-Dimethoxyphenyl)ethanone, acetic acid; Downstream Products: 6-hydroxyflavanone, 1,2,4-Benzenetriol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2',5'-Dihydroxyacetophenone (CAS 490-78-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-21445-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.