Xylometazoline hydrochloride
Also known as: 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-1H-imidazole hydrochloride, 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride, Otrivine hydrochloride, Novorin, Olynth, Galazolin, Neo-Synephrine II, Therapin, XYLOMETAZOLINE HCL, Xylometazoline HCl
Xylometazoline hydrochloride (CAS 1218-35-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C16H25ClN2 and a molecular weight of 280.836 g/mol. Key properties include a melting point of 131-133ºC, a boiling point of 394.2ºC at 760 mmHg and a flash point of 192.2ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1218-35-5
- Jingsj CID
- J-2110-4
- Molecular Formula
- C16H25ClN2
- Molecular Weight
- 280.836 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 131-133ºC |
|---|---|
| Boiling Point | 394.2ºC at 760 mmHg |
| Flash Point | 192.2ºC |
| Exact Mass | 280.170624 |
| PSA | 24.39000 |
| LogP | 3.71150 |
| Vapor Pressure | 4.56E-06mmHg at 25°C |
GHS Safety & Compliance
- H301 — Toxic if swallowed
Activity & Biological Data
| Additional Information | [1]. Eccles, R., et al., The nasal decongestant effect of xylometazoline in the common cold. Am J Rhinol, 2008. 22(5): p. 491-6. [2]. Haenisch, B., et al., Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline. Fundam Clin Pharmacol, 2010. 24(6): p. 729-39. |
|---|
Frequently Asked Questions
What is the CAS number of Xylometazoline hydrochloride?
The CAS number of Xylometazoline hydrochloride is 1218-35-5.
What are the molecular formula and molecular weight of Xylometazoline hydrochloride?
Xylometazoline hydrochloride has molecular formula C16H25ClN2 and molecular weight 280.836 g/mol.
Is Xylometazoline hydrochloride hazardous?
Xylometazoline hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Xylometazoline hydrochloride (CAS 1218-35-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2110-4 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.