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Dorzolamide

Also known as: Trusopt, 4S,6S-Dorzolamide, (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide, DORZOLAMIDE(SUBJECTTOPATENTFREE), MFCD00865636

Dorzolamide (CAS 120279-96-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C10H16N2O4S3 and a molecular weight of 324.44 g/mol. Key properties include a boiling point of 575.8ºC at 760 mmHg, a density of 1.53 g/cm3 and a flash point of 302ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
120279-96-1
Jingsj CID
J-20924-5
Molecular Formula
C10H16N2O4S3
Molecular Weight
324.44 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point575.8ºC at 760 mmHg
Density1.53 g/cm3
Flash Point302ºC
PSA151.33000
LogP4.66680
Refractive Index1.626
Storage Conditionsroom temp

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Rankin AJ, et al. Effects of ocular administration of ophthalmic 2% dorzolamide hydrochloride solution on aqueous humor flow rate and intraocular pressure in clinically normal cats. Am J Vet Res. 2012 Jul;73(7):1074-8. [2]. Sarup V, et al. Dorzolamide and timolol saves retinal ganglion cells in glaucomatous adult rats. J Ocul Pharmacol Ther. 2005 Dec;21(6):454-62.

Frequently Asked Questions

What is the CAS number of Dorzolamide?

The CAS number of Dorzolamide is 120279-96-1.

What are the molecular formula and molecular weight of Dorzolamide?

Dorzolamide has molecular formula C10H16N2O4S3 and molecular weight 324.44 g/mol.

Is Dorzolamide hazardous?

Dorzolamide has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Dorzolamide?

For Dorzolamide, Upstream Products: (6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-one, (4R,6S)-6-Methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol, (3S)-3-(2-thienylthio)butanoic acid; Downstream Products: Dorzolamide hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Dorzolamide (CAS 120279-96-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-20924-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.