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Tetraethylene glycol di-p-tosylate

Also known as: PROTAC Linker 16, Bis[2-(2-tosyloxyethoxy)ethyl] Ether, Bis[2-[2-(p-toluenesulfonyloxy)ethoxy]ethyl] Ether, Tetraethylene glycol bis(p-toluenesulfonate), Tetraethylene glycol ditosylate, 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate), Bis-TOS-PEG4

Tetraethylene glycol di-p-tosylate (CAS 37860-51-8) is a compound in the Solvents category listed in the Jingsj chemical database. It has the molecular formula C22H30O9S2 and a molecular weight of 502.59800 g/mol. Key properties include a boiling point of 635ºC at 760 mmHg, a density of 1.242 g/mL at 25ºC(lit.) and a flash point of >110.0 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.
37860-51-8
Jingsj CID
J-2076-8
Molecular Formula
C22H30O9S2
Molecular Weight
502.59800 g/mol
Category
Solvents
Last updated
11/3/2026

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Physicochemical Properties

Boiling Point635ºC at 760 mmHg
Density1.242 g/mL at 25ºC(lit.)
Flash Point>110.0 °C
Exact Mass502.13300
PSA131.19000
LogP4.62560
Refractive Indexn20/D 1.53(lit.)

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetPEGs
Additional Information[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Customs & Trade Information

HS Code2909309090
Summary2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Tetraethylene glycol di-p-tosylate?

The CAS number of Tetraethylene glycol di-p-tosylate is 37860-51-8.

What are the molecular formula and molecular weight of Tetraethylene glycol di-p-tosylate?

Tetraethylene glycol di-p-tosylate has molecular formula C22H30O9S2 and molecular weight 502.59800 g/mol.

Is Tetraethylene glycol di-p-tosylate hazardous?

Tetraethylene glycol di-p-tosylate has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Tetraethylene glycol di-p-tosylate (CAS 37860-51-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2076-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.