cholic acid
Also known as: (3a,5b,7a,12a)-3,7,12-Trihydroxycholan-24-oic acid, (3α,5β,7α,12α)-3,7,12-Trihydroxycholan-24-oic acid, (3α,5β,7α,8ξ,12α,20R)-3,7,12-Trihydroxycholan-24-oic acid, (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid, 17b-(1-Methyl-3-carboxypropyl)etiocholane-3a,7a,12a-triol, 3,7,12-TRIHYDROXYCHOLANIC ACID, 3,7,12-Trihydroxy-cholan-24-oic acid, 3A,7A,12A-TRIHYDROXY-5B-CHOLAN-24-OIC ACID, 3ALPHA, 7ALPHA, 12ALPHA-TRIHYDROXY-5BETA-CHOLANIC ACID, 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-IC ACID, 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OIC ACID, 3a,7a,12a-Trihydroxy-5b-cholan-24-oic Acid, 3a,7a,12a-Trihydroxy-5b-cholanic Acid, 3a,7a,12a-Trihydroxy-5b-cholanoic acid, 3a,7a,12a-Trihydroxy-b-cholanic acid, 3a,7a,12a-Trihydroxy-β-cholanic acid, 3a,7a,12a-Trihydroxycholanic acid, 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid, 5b-Cholanic acid-3a,7a,12a-triol, 5b-Cholic acid
cholic acid (CAS 81-25-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C24H40O5 and a molecular weight of 408.571 g/mol. Key properties include a melting point of 197-202 ºC, a boiling point of 583.9±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 321.0±26.6 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 81-25-4
- Jingsj CID
- J-20690-7
- Molecular Formula
- C24H40O5
- Molecular Weight
- 408.571 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 197-202 ºC |
|---|---|
| Boiling Point | 583.9±50.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 321.0±26.6 °C |
| Exact Mass | 408.287567 |
| PSA | 97.99000 |
| LogP | 2.62 |
| Vapor Pressure | 0.0±3.7 mmHg at 25°C |
| Refractive Index | 1.558 |
| Additional Property | 0.28 g/L (15 ºC) |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. Li Y, et al. Mechanism of hepatic targeting via oral administration of DSPE-PEG-Cholic acid-modified nanoliposomes. Int J Nanomedicine. 2017 Feb 28;12:1673-1684. [2]. Pan X, et al. Cholic acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice. Drug Metab Dispos. 2017 Apr;45(4):346-352. |
Customs & Trade Information
| HS Code | 2942000000 |
|---|
Frequently Asked Questions
What is the CAS number of cholic acid?
The CAS number of cholic acid is 81-25-4.
What are the molecular formula and molecular weight of cholic acid?
cholic acid has molecular formula C24H40O5 and molecular weight 408.571 g/mol.
Is cholic acid hazardous?
cholic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of cholic acid?
For cholic acid, Upstream Products: 7-Ketodeoxycholic acid, Lithocholic acid, Methyl cholate; Downstream Products: Sodium cholate, 3α-Hydroxy-7-oxo-5β-cholanic acid, Chenodeoxycholic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "cholic acid (CAS 81-25-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-20690-7 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.