Suberoyl bis-hydroxamic acid

Also known as: N1,N8-Dihydroxyoctanediamide, N,N'-Dihydroxyoctanediamide, Suberodihydroxamic acid, Suberic bishydroxamate, Octane-1,8-dihydroxamic acid, SBHA, ODHA

Suberoyl bis-hydroxamic acid (CAS 38937-66-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H16N2O4 and a molecular weight of 204.224 g/mol. Key properties include a melting point of 153-155ºC(lit.) and a density of 1.2±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 38937-66-5
Jingsj CID: J-20114-9
Molecular Formula: C₈H₁₆N₂O₄
Molecular Weight: 204.224 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	153-155ºC(lit.)
Density	1.2±0.1 g/cm3
Exact Mass	204.111008
PSA	98.66000
LogP	-1.81
Appearance	lyophilized powder
Refractive Index	1.502
Storage Conditions	−20°C
Additional Property	H2O: soluble

Activity & Biological Data

Target	HDAC1:0.25 μM (IC50) HDAC3:0.30 μM (IC50)
Additional Information	[1]. Jiri Neuzil, et al. Sensitization of Mesothelioma to TRAIL Apoptosis by Inhibition of Histone Deacetylase: Role of Bcl-xL Down-Regulation. Biochem Biophys Res Commun. 2004 Jan 30;314(1):186-91. [2]. V M Richon, et al. A Class of Hybrid Polar Inducers of Transformed Cell Differentiation Inhibits Histone Deacetylases.Proc Natl Acad Sci U S A [3]. Li Ning, et al. Suberoyl Bishydroxamic Acid Activates notch1 Signaling and Suppresses Tumor Progression in an Animal Model of Medullary Thyroid Carcinoma. Ann Surg Oncol. 2008 Sep;15(9):2600-5.

Target

HDAC1:0.25 μM (IC50) HDAC3:0.30 μM (IC50)

Additional Information

[1]. Jiri Neuzil, et al. Sensitization of Mesothelioma to TRAIL Apoptosis by Inhibition of Histone Deacetylase: Role of Bcl-xL Down-Regulation. Biochem Biophys Res Commun. 2004 Jan 30;314(1):186-91. [2]. V M Richon, et al. A Class of Hybrid Polar Inducers of Transformed Cell Differentiation Inhibits Histone Deacetylases.Proc Natl Acad Sci U S A [3]. Li Ning, et al. Suberoyl Bishydroxamic Acid Activates notch1 Signaling and Suppresses Tumor Progression in an Animal Model of Medullary Thyroid Carcinoma. Ann Surg Oncol. 2008 Sep;15(9):2600-5.

Customs & Trade Information

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Suberoyl bis-hydroxamic acid?

The CAS number of Suberoyl bis-hydroxamic acid is 38937-66-5.

What are the molecular formula and molecular weight of Suberoyl bis-hydroxamic acid?

Suberoyl bis-hydroxamic acid has molecular formula C8H16N2O4 and molecular weight 204.224 g/mol.

What are the upstream and downstream products of Suberoyl bis-hydroxamic acid?

For Suberoyl bis-hydroxamic acid, Upstream Products: Dimethyl suberate, Diethyl suberate, Suberic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Suberoyl bis-hydroxamic acid (CAS 38937-66-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-20114-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.