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Methyl 2-aminothiophene-3-carboxylate

Also known as: Methyl 2-amino-3-thenoate, Methyl 2-amino-3-thiophenecarboxylate, 2-Amino-3-carbomethoxythiophene, 2-Amino-3-methoxycarbonylthiophene, 3-Thiophenecarboxylic acid, 2-amino-, methyl ester, 2-Amino-thiophene-3-carboxylic acid methyl ester

Methyl 2-aminothiophene-3-carboxylate (CAS 4651-81-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H7NO2S and a molecular weight of 157.190 g/mol. Key properties include a melting point of 76-81 °C(lit.), a boiling point of 259.5±20.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 110.7±21.8 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
4651-81-4
Jingsj CID
J-1994072-8
Molecular Formula
C6H7NO2S
Molecular Weight
157.190 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point76-81 °C(lit.)
Boiling Point259.5±20.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point110.7±21.8 °C
Exact Mass157.019745
PSA80.56000
LogP2.35
Vapor Pressure0.0±0.5 mmHg at 25°C
Refractive Index1.598

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Methyl 2-aminothiophene-3-carboxylate?

The CAS number of Methyl 2-aminothiophene-3-carboxylate is 4651-81-4.

What are the molecular formula and molecular weight of Methyl 2-aminothiophene-3-carboxylate?

Methyl 2-aminothiophene-3-carboxylate has molecular formula C6H7NO2S and molecular weight 157.190 g/mol.

Is Methyl 2-aminothiophene-3-carboxylate hazardous?

Methyl 2-aminothiophene-3-carboxylate has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Methyl 2-aminothiophene-3-carboxylate?

For Methyl 2-aminothiophene-3-carboxylate, Upstream Products: 1,4-Dithiane-2,5-diol, Methyl cyanoacetate, ch3cho; Downstream Products: 1H-Pyrazolo[3,4-c]pyridazin-3(2H)-one, thieno[2,3-d]pyrimidine-2,4-diol, 2,4-Dichlorothieno[2,3-d]pyrimidine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Methyl 2-aminothiophene-3-carboxylate (CAS 4651-81-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1994072-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.