Flecainide

Also known as: Flecainide, Flecanide, Flecaine, FLECAINTDE BASE, N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide, N-(2-piperidylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide, N-(Piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide, 2,5-bis-(2,2,2-Trifluoroethoxy)-n-(2-piperidyl-methyl)-benzamide, Benzamide, N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-, MFCD00864713

Flecainide (CAS 54143-55-4) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C17H20F6N2O3 and a molecular weight of 414.34300 g/mol. Key properties include a melting point of 105-1070C, a boiling point of 434.9ºC at 760 mmHg, a density of 1.286 g/cm3 and a flash point of 216.8ºC. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 54143-55-4
Jingsj CID: J-1993849-3
Molecular Formula: C₁₇H₂₀F₆N₂O₃
Molecular Weight: 414.34300 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	105-1070C
Boiling Point	434.9ºC at 760 mmHg
Density	1.286 g/cm3
Flash Point	216.8ºC
Exact Mass	414.13800
PSA	59.59000
LogP	4.16040
Storage Conditions	Refrigerator

GHS Safety & Compliance

Flammable / Acute Toxicity / Health HazardSignal word: Danger

H225 — Highly flammable liquid and vapour
H301 — Toxic if swallowed
H311 — Toxic in contact with skin
H331 — Toxic if inhaled
H370 — Causes damage to organs

Activity & Biological Data

Additional Information	[1]. Echt DS, et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med. 1991 Mar 21;324(12):781-8. [2]. Aliot E, et al. Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace. 2011 Feb;13(2):161-73. [3]. Allan LD, et al. Flecainide in the treatment of fetal tachycardias. Br Heart J. 1991 Jan;65(1):46-8.

Additional Information

[1]. Echt DS, et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med. 1991 Mar 21;324(12):781-8. [2]. Aliot E, et al. Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace. 2011 Feb;13(2):161-73. [3]. Allan LD, et al. Flecainide in the treatment of fetal tachycardias. Br Heart J. 1991 Jan;65(1):46-8.

Frequently Asked Questions

What is the CAS number of Flecainide?

The CAS number of Flecainide is 54143-55-4.

What are the molecular formula and molecular weight of Flecainide?

Flecainide has molecular formula C17H20F6N2O3 and molecular weight 414.34300 g/mol.

Is Flecainide hazardous?

Flecainide has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.

What are the upstream and downstream products of Flecainide?

For Flecainide, Upstream Products: 2-(Aminomethyl)piperidine, Methyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate; Downstream Products: Flecainide acetate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Flecainide (CAS 54143-55-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1993849-3 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.