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Tetraethyl pyrophosphite

Also known as: Bis(diethoxyphosphino) ether, Bis(phosphorous acid diethyl)anhydride, Diphosphorous acid tetraethyl ester, Oxybis(diethoxyphosphine), Oxybis(phosphonous acid diethyl) ester, diethoxyphosphanyl diethyl phosphite, tetraethyldiphosphite

Tetraethyl pyrophosphite (CAS 21646-99-1) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H20O5P2 and a molecular weight of 258.18900 g/mol. Key properties include a boiling point of 237.9ºC at 760mmHg, a density of 1.057 g/mL at 25 °C(lit.) and a flash point of 115.2ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
21646-99-1
Jingsj CID
J-1993530-9
Molecular Formula
C8H20O5P2
Molecular Weight
258.18900 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point237.9ºC at 760mmHg
Density1.057 g/mL at 25 °C(lit.)
Flash Point115.2ºC
Exact Mass258.07900
PSA73.33000
LogP3.60280
Vapor Pressure0.0674mmHg at 25°C
Refractive Indexn20/D 1.434(lit.)

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Frequently Asked Questions

What is the CAS number of Tetraethyl pyrophosphite?

The CAS number of Tetraethyl pyrophosphite is 21646-99-1.

What are the molecular formula and molecular weight of Tetraethyl pyrophosphite?

Tetraethyl pyrophosphite has molecular formula C8H20O5P2 and molecular weight 258.18900 g/mol.

Is Tetraethyl pyrophosphite hazardous?

Tetraethyl pyrophosphite has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Tetraethyl pyrophosphite?

For Tetraethyl pyrophosphite, Upstream Products: Diethyl phosphite, Diethyl chlorophosphite, Triethyl phosphite; Downstream Products: Diethyl acetylphosphonate, Diethyl chlorophosphite, Diethyl (trichloromethyl)phosphonate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Tetraethyl pyrophosphite (CAS 21646-99-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1993530-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.