Loperamide
Also known as: 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide, 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide, Imodium, Kaopectate II, Loperamida, Loperamidum, ADL 2-1294, MFCD00600388, EINECS 258-416-5
Loperamide (CAS 53179-11-6) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C29H33ClN2O2 and a molecular weight of 477.04 g/mol. Key properties include a boiling point of 647.2ºC at 760 mmHg, a density of 1.187g/cm3 and a flash point of 345.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 53179-11-6
- Jingsj CID
- J-1991281-3
- Molecular Formula
- C29H33ClN2O2
- Molecular Weight
- 477.04 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 647.2ºC at 760 mmHg |
|---|---|
| Density | 1.187g/cm3 |
| Flash Point | 345.2ºC |
| Exact Mass | 476.22300 |
| PSA | 43.78000 |
| LogP | 5.02590 |
| Refractive Index | 1.6 |
Activity & Biological Data
| Target | Ki: 3 nM (μ opioid receptor), 48 nM (δ opioid receptor), 1156 nM (κ opioid receptor)[1] |
|---|---|
| Additional Information | [1]. DeHaven-Hudkins DL, et al. Loperamide (ADL 2-1294), an opioid antihyperalgesic agent with peripheral selectivity. J Pharmacol Exp Ther. 1999 Apr;289(1):494-502. |
Customs & Trade Information
| HS Code | 29252000 |
|---|
Frequently Asked Questions
What is the CAS number of Loperamide?
The CAS number of Loperamide is 53179-11-6.
What are the molecular formula and molecular weight of Loperamide?
Loperamide has molecular formula C29H33ClN2O2 and molecular weight 477.04 g/mol.
What are the upstream and downstream products of Loperamide?
For Loperamide, Upstream Products: 4-(4-Chlorophenyl)piperidin-4-ol, 3,3-Diphenyltetrahydrofuran-2-ylidene(dimethyl)ammonium bromide, 4-Bromo-2,2-diphenylbutyric acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Loperamide (CAS 53179-11-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1991281-3 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.