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5-Methoxy-2-mercaptobenzimidazole

Also known as: 2-Mercapto-5-methoxybenzimidazole, 2-Mercapto-5-methoxy-1H-benzimidazole, 5-Methoxy-2-benzimidazolethiol, 5-Methoxy-1H-benzo[d]imidazole-2-thiol, 5-Methoxy-2-thiobenzimidazole, 5-Methoxybenzimidazole-2-thiol, 2H-Benzimidazole-2-thione, 1,3-dihydro-5-methoxy-, Esomeprazole Impurity 1, H 118/87, MFCD00134581, EINECS 253-326-2

5-Methoxy-2-mercaptobenzimidazole (CAS 37052-78-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C8H8N2OS and a molecular weight of 180.227 g/mol. Key properties include a melting point of 261-263 °C(lit.), a boiling point of 309.4±44.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 140.9±28.4 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
37052-78-1
Jingsj CID
J-1990713-2
Molecular Formula
C8H8N2OS
Molecular Weight
180.227 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point261-263 °C(lit.)
Boiling Point309.4±44.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point140.9±28.4 °C
Exact Mass180.035736
PSA72.90000
LogP1.92
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.695
Additional Propertyinsoluble

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Witold Ciesielski, et al. Iodimetric Determination of 2-Benzimidazolethiols and 2-Benzothiazolethiols. Chem. Anal. (Warsaw), 49, 577 (2004).

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 5-Methoxy-2-mercaptobenzimidazole?

The CAS number of 5-Methoxy-2-mercaptobenzimidazole is 37052-78-1.

What are the molecular formula and molecular weight of 5-Methoxy-2-mercaptobenzimidazole?

5-Methoxy-2-mercaptobenzimidazole has molecular formula C8H8N2OS and molecular weight 180.227 g/mol.

Is 5-Methoxy-2-mercaptobenzimidazole hazardous?

5-Methoxy-2-mercaptobenzimidazole has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 5-Methoxy-2-mercaptobenzimidazole?

For 5-Methoxy-2-mercaptobenzimidazole, Upstream Products: Carbon disulphide, N-(2-Amino-4-methoxyphenyl)acetamide, 4-Methoxy-o-phenylenediamine; Downstream Products: Ufiprazole, 5-Methoxy-2-[[(3,5-dimethyl-4-nitro-2-pyridinyl)methyl]thio]-1H-benzimidazole, 5-Methoxy-2-(methylthio)benzimidazole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "5-Methoxy-2-mercaptobenzimidazole (CAS 37052-78-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1990713-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.