Nordihydroguaiaretic acid

去甲二氢愈创木酸

Also known as: NDGA, Masoprocol, 4,4'-(2,3-Dimethyltetramethylene)dipyrocatechol, 1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane, 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis(1,2-benzenediol), Actinex, Dihydronorguaiaretic acid, Dinorguaiaretic acid, dihydro-, beta,gamma-Dimethyl-alpha,delta-bis(3,4-dihydroxyphenyl)butane, meso-Nordihydroguaiaretic acid, 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-

Nordihydroguaiaretic acid (CAS 500-38-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C18H22O4 and a molecular weight of 302.365 g/mol. It is also known as NDGA, Masoprocol and 4,4'-(2,3-Dimethyltetramethylene)dipyrocatechol. Key properties include a melting point of 184-189ºC, a boiling point of 526.5±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 247.8±23.3 °C. GHS signal word: Warning. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
500-38-9
Jingsj CID
J-1990119-0
Molecular Formula
C18H22O4
Chinese Name
去甲二氢愈创木酸
Molecular Weight
302.365 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point184-189ºC
Boiling Point526.5±45.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point247.8±23.3 °C

GHS Safety & Compliance

IrritantSignal word: Warning

Frequently Asked Questions

What is the CAS number of Nordihydroguaiaretic acid?

The CAS number of Nordihydroguaiaretic acid is 500-38-9.

What are the molecular formula and molecular weight of Nordihydroguaiaretic acid?

Nordihydroguaiaretic acid has molecular formula C18H22O4 and molecular weight 302.365 g/mol.

Is Nordihydroguaiaretic acid hazardous?

Nordihydroguaiaretic acid has GHS signal word Warning.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Nordihydroguaiaretic acid (CAS 500-38-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1990119-0 (accessed 2026-10-24).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.