FK-3311

Also known as: N-[4-Acetyl-2-(2,4-difluorophenoxy)phenyl]methanesulfonamide, Methanesulfonamide, N-[4-acetyl-2-(2,4-difluorophenoxy)phenyl]-, COX-2 Inhibitor V, FK3311, CS-1073

FK-3311 (CAS 116686-15-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C15H13F2NO4S and a molecular weight of 341.330 g/mol. Key properties include a boiling point of 431.3±55.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 214.6±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 116686-15-8
Jingsj CID: J-1987551-5
Molecular Formula: C₁₅H₁₃F₂NO₄S
Molecular Weight: 341.330 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	431.3±55.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	214.6±31.5 °C
Exact Mass	341.053345
PSA	80.85000
LogP	3.22
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.579
Storage Conditions	2-8℃

Activity & Biological Data

Target	COX-2
Additional Information	[1]. Nakamura K, Ochi T, Matsuo M. [Stereoselective synthesis and pharmacological properties of metabolites of new antiinflammatory agent. 4'-Acetyl-2'-(2,4-difluorophenoxy)methanesulfonanilide (FK3311)]. Yakugaku Zasshi. 1995 Nov;115(11):928-36. [2]. Sunose Y, Takeyoshi I, Tsutsumi H, Effects of FK3311 on pulmonary ischemia-reperfusion injury in a canine model. J Surg Res. 2001 Feb;95(2):167-73. [3]. Oshima K, Yabata Y, Yoshinari D, The effects of cyclooxygenase (COX)-2 inhibition on ischemia-reperfusion injury in liver transplantation. J Invest Surg. 2009 Jul-Aug;22(4):239-45.

Target

COX-2

Additional Information

[1]. Nakamura K, Ochi T, Matsuo M. [Stereoselective synthesis and pharmacological properties of metabolites of new antiinflammatory agent. 4'-Acetyl-2'-(2,4-difluorophenoxy)methanesulfonanilide (FK3311)]. Yakugaku Zasshi. 1995 Nov;115(11):928-36. [2]. Sunose Y, Takeyoshi I, Tsutsumi H, Effects of FK3311 on pulmonary ischemia-reperfusion injury in a canine model. J Surg Res. 2001 Feb;95(2):167-73. [3]. Oshima K, Yabata Y, Yoshinari D, The effects of cyclooxygenase (COX)-2 inhibition on ischemia-reperfusion injury in liver transplantation. J Invest Surg. 2009 Jul-Aug;22(4):239-45.

Frequently Asked Questions

What is the CAS number of FK-3311?

The CAS number of FK-3311 is 116686-15-8.

What are the molecular formula and molecular weight of FK-3311?

FK-3311 has molecular formula C15H13F2NO4S and molecular weight 341.330 g/mol.

What are the upstream and downstream products of FK-3311?

For FK-3311, Upstream Products: 1-(4-Amino-3-chlorophenyl)ethanone, 1-(3-Chloro-4-nitrophenyl)ethanone, 2,4-Difluorophenol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "FK-3311 (CAS 116686-15-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987551-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.