1,4-Dimethoxy-9(10H)-acridinethione

Also known as: NSC 625987, 1,4-Dimethoxy-9-thio(10H)-acridone, 1,4-dimethoxy-10H-acridine-9-thione, 9(10H)-Acridinethione, 1,4-dimethoxy-, Cdk4 Inhibitor II, Tocris-2152

1,4-Dimethoxy-9(10H)-acridinethione (CAS 141992-47-4) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C15H13NO2S and a molecular weight of 271.33400 g/mol. Key properties include a boiling point of 460.4ºC at 760 mmHg, a density of 1.32g/cm3 and a flash point of 232.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 141992-47-4
Jingsj CID: J-1987518-4
Molecular Formula: C₁₅H₁₃NO₂S
Molecular Weight: 271.33400 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	460.4ºC at 760 mmHg
Density	1.32g/cm3
Flash Point	232.2ºC
Exact Mass	271.06700
PSA	66.34000
LogP	4.06780
Vapor Pressure	1.17E-08mmHg at 25°C
Refractive Index	1.683

Activity & Biological Data

Target	CDK4/D1:0.2 μM (IC50)
Additional Information	[1]. A Kubo, et al. The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4. Clin Cancer Res. 1999 Dec;5(12):4279-86. [2]. Jasmine El Andalousi, et al.Natriuretic peptide receptor-C agonist attenuates the expression of cell cycle proteins and proliferation of vascular smooth muscle cells from spontaneously hypertensive rats: role of Gi proteins and MAPkinase/PI3kinase signaling. PLoS One. 2013 Oct 14;8(10):e76183.

Target

CDK4/D1:0.2 μM (IC50)

Additional Information

[1]. A Kubo, et al. The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4. Clin Cancer Res. 1999 Dec;5(12):4279-86. [2]. Jasmine El Andalousi, et al.Natriuretic peptide receptor-C agonist attenuates the expression of cell cycle proteins and proliferation of vascular smooth muscle cells from spontaneously hypertensive rats: role of Gi proteins and MAPkinase/PI3kinase signaling. PLoS One. 2013 Oct 14;8(10):e76183.

Frequently Asked Questions

What is the CAS number of 1,4-Dimethoxy-9(10H)-acridinethione?

The CAS number of 1,4-Dimethoxy-9(10H)-acridinethione is 141992-47-4.

What are the molecular formula and molecular weight of 1,4-Dimethoxy-9(10H)-acridinethione?

1,4-Dimethoxy-9(10H)-acridinethione has molecular formula C15H13NO2S and molecular weight 271.33400 g/mol.

What are the upstream and downstream products of 1,4-Dimethoxy-9(10H)-acridinethione?

For 1,4-Dimethoxy-9(10H)-acridinethione, Upstream Products: 2,5-Dimethoxyaniline, 2-Chlorobenzoic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "1,4-Dimethoxy-9(10H)-acridinethione (CAS 141992-47-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987518-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.