8-M-PDOT

Also known as: AH-002, AH 002, 8-METHOXY-2-PROPIONAMIDOTETRALIN, 8-Methoxy-2-propionamidotetralin, N-[(2R)-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl]propanamide, Propanamide, N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-, 8M-PDOT, 8MPDOT

8-M-PDOT (CAS 134865-70-6) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C14H19NO2 and a molecular weight of 233.30600 g/mol. Key properties include a boiling point of 447.8ºC at 760 mmHg, a density of 1.09g/cm3 and a flash point of 224.6ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 134865-70-6
Jingsj CID: J-1987501-5
Molecular Formula: C₁₄H₁₉NO₂
Molecular Weight: 233.30600 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	447.8ºC at 760 mmHg
Density	1.09g/cm3
Flash Point	224.6ºC
Exact Mass	233.14200
PSA	38.33000
LogP	2.46960
Vapor Pressure	3.27E-08mmHg at 25°C
Refractive Index	1.542

Activity & Biological Data

Target	pKi: 8.23 (Melatonin MT2 receptor) and 8.95 (Melatonin MT1 receptor)[2]
Additional Information	[1]. Browning C, et al. Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) receptors. Br J Pharmacol. 2000 Mar;129(5):877-86. [2]. Noseda AC, et al. REM sleep deprivation promotes a dopaminergic influence in the striatal MT2 anxiolytic-like effects. Sleep Sci. 2016 Jan-Mar;9(1):47-54.

Frequently Asked Questions

What is the CAS number of 8-M-PDOT?

The CAS number of 8-M-PDOT is 134865-70-6.

What are the molecular formula and molecular weight of 8-M-PDOT?

8-M-PDOT has molecular formula C14H19NO2 and molecular weight 233.30600 g/mol.

What are the upstream and downstream products of 8-M-PDOT?

For 8-M-PDOT, Upstream Products: Propionic anhydride, 2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalene hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "8-M-PDOT (CAS 134865-70-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987501-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.