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5α-Dihydroprogesterone

Also known as: 5-alpha-dihydroprogesterone, 5α-pregnane-3,20-dione, 5a-pregnane-3,20-dione, allopregnane-3,20-dione, allopregnanedione, 3,20-dioxo-5α-pregnane, (5α)-pregnane-3,20-dione, pregnane-3,20-dione, 5-α-pregnane-3,20-dione

5α-Dihydroprogesterone (CAS 566-65-4) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C21H32O2 and a molecular weight of 316.478 g/mol. Key properties include a melting point of 204 °C, a boiling point of 429.2±38.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 160.3±23.8 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
566-65-4
Jingsj CID
J-1987420-5
Molecular Formula
C21H32O2
Molecular Weight
316.478 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point204 °C
Boiling Point429.2±38.0 °C at 760 mmHg
Density1.0±0.1 g/cm3
Flash Point160.3±23.8 °C
Exact Mass316.240234
PSA34.14000
LogP4.31
Vapor Pressure0.0±1.0 mmHg at 25°C
Refractive Index1.516

Activity & Biological Data

TargetHuman Endogenous Metabolite
Additional Information[1]. Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16(1):7-14.

Frequently Asked Questions

What is the CAS number of 5α-Dihydroprogesterone?

The CAS number of 5α-Dihydroprogesterone is 566-65-4.

What are the molecular formula and molecular weight of 5α-Dihydroprogesterone?

5α-Dihydroprogesterone has molecular formula C21H32O2 and molecular weight 316.478 g/mol.

What are the upstream and downstream products of 5α-Dihydroprogesterone?

For 5α-Dihydroprogesterone, Upstream Products: Progesterone, Allopregnanolone, Pregnenolone; Downstream Products: 3α,21-dihydroxy-5α-pregnan-20-one, Allopregnanolone, Allopregnanolone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "5α-Dihydroprogesterone (CAS 566-65-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987420-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.