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O-tert-Butyl-L-threonine

Also known as: H-Thr(tBu)-OH, (2S,3R)-2-amino-3-(tert-butoxy)butanoic acid, (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoic acid, H-Thr(Bu)-OH, O-(1,1-Dimethylethyl)-L-threonine, L-Threonine, O-(1,1-dimethylethyl)-, Threonine tert-butyl ether, O-(2-Methyl-2-propanyl)-L-threonine

O-tert-Butyl-L-threonine (CAS 4378-13-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H17NO3 and a molecular weight of 175.225 g/mol. Key properties include a melting point of 244-247ºC, a boiling point of 275.3±30.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 120.3±24.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
4378-13-6
Jingsj CID
J-1987322-4
Molecular Formula
C8H17NO3
Molecular Weight
175.225 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point244-247ºC
Boiling Point275.3±30.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point120.3±24.6 °C
Exact Mass175.120850
PSA72.55000
LogP1.22
AppearanceSolid
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.464
Storage ConditionsStore at RT.

Activity & Biological Data

Additional Information[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Customs & Trade Information

HS Code2922509090
Summary2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of O-tert-Butyl-L-threonine?

The CAS number of O-tert-Butyl-L-threonine is 4378-13-6.

What are the molecular formula and molecular weight of O-tert-Butyl-L-threonine?

O-tert-Butyl-L-threonine has molecular formula C8H17NO3 and molecular weight 175.225 g/mol.

What are the upstream and downstream products of O-tert-Butyl-L-threonine?

For O-tert-Butyl-L-threonine, Upstream Products: Fmoc-Thr(tBu)-OH, Isobutylene; Downstream Products: Fmoc-Thr(tBu)-OH, Boc-O-tert-butyl-L-threonine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "O-tert-Butyl-L-threonine (CAS 4378-13-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987322-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.