Montelukast sodium

Also known as: Montelukast Sodium, Singulair, MK-476, Montelukast monosodium salt, Montelukast sodium salt, Montelukast Sodium Hydrate, Sodium 1-((((R)-m-((E)-2-(7-Chloro-2-quinolyl)vinyl)-a-(o-(1-hydroxy-1-methylethyl)phenethyl)benzyl)thio)methyl)cyclopropaneacetate, Sodium {1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)vinyl]phenyl}-3-[2-(2-hydroxy-2-propanyl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetate, Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-, sodium salt (1:1), sodium (1-{[(1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl)sulfanyl]methyl}cyclopropyl)acetate, sodium (R,E)-2-(1-(1-(3-(-(7-chloroquinolin-2-yl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylthio)cyclopropyl)acetate, Methyl-[E]-(+)-1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)-ethenyl]phenyl]-3-[2-(1-hydroxyl-1-methylethyl)phenyl]propyl]mercapto]methyl]cyclopropane acetic acid sodium, Montelukast (sodium), Montelukast, Sodium Salt, sodium,2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate

Montelukast sodium (CAS 151767-02-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C35H35ClNNaO3S and a molecular weight of 608.165 g/mol. Key properties include a melting point of 115 °C(dec.), a boiling point of 750.5ºC at 760mmHg and a flash point of 407.7ºC. It is classified under GHS with signal word Danger and hazard statements H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 151767-02-1
Jingsj CID: J-1987132-0
Molecular Formula: C₃₅H₃₅ClNNaO₃S
Molecular Weight: 608.165 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	115 °C(dec.)
Boiling Point	750.5ºC at 760mmHg
Flash Point	407.7ºC
Exact Mass	607.192383
PSA	98.55000
LogP	7.61330
Appearance	white to tan
Storage Conditions	-20°C Freezer, Under Inert Atmosphere
Additional Property	DMSO: ≥8mg/mL at 60°C

GHS Safety & Compliance

Corrosion / Health HazardSignal word: Danger

H318 — Causes serious eye damage

Activity & Biological Data

Target	CysLT1 Autophagy
Additional Information	[1]. Mullol J, et al. Montelukast?reduces eosinophilic inflammation by inhibiting both epithelial cell cytokine secretion (GM-CSF, IL-6, IL-8) and eosinophil survival. J Biol Regul Homeost Agents.?2010 Oct-Dec;24(4):403-11. [2]. Zhang HP, et al. Montelukast for prevention and treatment of asthma exacerbations in adults: Systematic review and meta-analysis. Allergy Asthma Proc. 2014 Jul-Aug;35(4):278-87. [3]. Wei B, et al. Effect of montelukast on the expression of neurokinin-1 receptor in young asthmatic rats with airway remodeling. Zhongguo Dang Dai Er Ke Za Zhi. 2013 Apr;15(4):298-301. [4]. Lai J, et al. Montelukast targeting the cysteinyl leukotriene receptor 1 ameliorates Aβ1-42-induced memory impairment and neuroinflammatory and apoptotic responses in mice. Neuropharmacology. 2014 Apr;79:707-14.

Target

CysLT1 Autophagy

Additional Information

[1]. Mullol J, et al. Montelukast?reduces eosinophilic inflammation by inhibiting both epithelial cell cytokine secretion (GM-CSF, IL-6, IL-8) and eosinophil survival. J Biol Regul Homeost Agents.?2010 Oct-Dec;24(4):403-11. [2]. Zhang HP, et al. Montelukast for prevention and treatment of asthma exacerbations in adults: Systematic review and meta-analysis. Allergy Asthma Proc. 2014 Jul-Aug;35(4):278-87. [3]. Wei B, et al. Effect of montelukast on the expression of neurokinin-1 receptor in young asthmatic rats with airway remodeling. Zhongguo Dang Dai Er Ke Za Zhi. 2013 Apr;15(4):298-301. [4]. Lai J, et al. Montelukast targeting the cysteinyl leukotriene receptor 1 ameliorates Aβ1-42-induced memory impairment and neuroinflammatory and apoptotic responses in mice. Neuropharmacology. 2014 Apr;79:707-14.

Customs & Trade Information

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Montelukast sodium?

The CAS number of Montelukast sodium is 151767-02-1.

What are the molecular formula and molecular weight of Montelukast sodium?

Montelukast sodium has molecular formula C35H35ClNNaO3S and molecular weight 608.165 g/mol.

Is Montelukast sodium hazardous?

Montelukast sodium has GHS signal word Danger and hazard statements H318 — Causes serious eye damage.

What are the upstream and downstream products of Montelukast sodium?

For Montelukast sodium, Upstream Products: Montelukast Dicyclohexylamine Salt, Montelukast; Downstream Products: Montelukast, Montelukast Bis-sulfide, Montelukast EP Impurity E.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Montelukast sodium (CAS 151767-02-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987132-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.