Darunavir ethanolate

Also known as: Darunavir Ethanolate(Prezista), TMC114 ethanolate, UNII-33O78XF0BW, Darunavir (Ethanolate), DARUNAVIR ETHANOLATE(PREZISTA) TMC114, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate compound with ethanol (1:1), Darunavir(TMC-114,UIC 94017) Ethanolate, [14C]-Darunavir ethanolate

Darunavir ethanolate (CAS 635728-49-3) is a compound in the Solvents category listed in the Jingsj chemical database. It has the molecular formula C29H43N3O8S and a molecular weight of 593.732 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 635728-49-3
Jingsj CID: J-1986958-6
Molecular Formula: C₂₉H₄₃N₃O₈S
Molecular Weight: 593.732 g/mol
Category: Solvents
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Exact Mass	593.277100
PSA	169.03000
LogP	4.42680
Storage Conditions	-20℃

Activity & Biological Data

Target	Ki: 1 nM (WT HIV-1 protease)[1]
Additional Information	[1]. Tie Y, et al. High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains. J Mol Biol. 2004 Apr 23;338(2):341-52. [2]. McKeage K, et al. Darunavir: a review of its use in the management of HIV infection in adults. Drugs. 2009;69(4):477-503. [3]. Bhalekar MR, et al. In-vivo bioavailability and lymphatic uptake evaluation of lipid nanoparticulates of darunavir. Drug Deliv. 2016 Sep;23(7):2581-2586.

Target

Ki: 1 nM (WT HIV-1 protease)[1]

Additional Information

[1]. Tie Y, et al. High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains. J Mol Biol. 2004 Apr 23;338(2):341-52. [2]. McKeage K, et al. Darunavir: a review of its use in the management of HIV infection in adults. Drugs. 2009;69(4):477-503. [3]. Bhalekar MR, et al. In-vivo bioavailability and lymphatic uptake evaluation of lipid nanoparticulates of darunavir. Drug Deliv. 2016 Sep;23(7):2581-2586.

Frequently Asked Questions

What is the CAS number of Darunavir ethanolate?

The CAS number of Darunavir ethanolate is 635728-49-3.

What are the molecular formula and molecular weight of Darunavir ethanolate?

Darunavir ethanolate has molecular formula C29H43N3O8S and molecular weight 593.732 g/mol.

What are the upstream and downstream products of Darunavir ethanolate?

For Darunavir ethanolate, Upstream Products: Ethanol, 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide, (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Darunavir ethanolate (CAS 635728-49-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1986958-6 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.