Tenofovir disoproxil

Also known as: Bis(((isopropoxycarbonyl)oxy)methyl) (((1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy)methyl)phosphonate, Bis{[(isopropoxycarbonyl)oxy]methyl} ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate, Bis{[(isopropoxycarbonyl)oxy]methyl} ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate, Carbonic acid, [[[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl][[[(1-methylethoxy)carbonyl]oxy]methoxy]phosphinyl]oxy]methyl 1-methylethyl ester, Pmpa prodrug, Tdf, Tenofovir (Disoproxil), bis({[(propan-2-yloxy)carbonyl]oxy}methyl) ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate

Tenofovir disoproxil (CAS 201341-05-1) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C19H30N5O10P and a molecular weight of 519.443 g/mol. Key properties include a boiling point of 642.7±65.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 342.5±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 201341-05-1
Jingsj CID: J-1986854-1
Molecular Formula: C₁₉H₃₀N₅O₁₀P
Molecular Weight: 519.443 g/mol
Category: Esters
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Boiling Point	642.7±65.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	342.5±34.3 °C
Exact Mass	519.173035
PSA	195.25000
LogP	2.04
Vapor Pressure	0.0±1.9 mmHg at 25°C
Refractive Index	1.578
Storage Conditions	-20°C

Activity & Biological Data

Additional Information	[1]. Murphy RA, et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3). [2]. Musumeci G, et al. M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures. Sci Rep. 2017 Feb 1;7:41018. [3]. Wahl A, et al. Predicting HIV Pre-exposure Prophylaxis Efficacy for Women using a Preclinical Pharmacokinetic-Pharmacodynamic In Vivo Model. Sci Rep. 2017 Feb 1;7:41098. [4]. Menne S, Cote PJ, Korba BE, Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection. Antimicrob Agents Chemother. 2005 Jul;49(7):2720-8.

Additional Information

[1]. Murphy RA, et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3). [2]. Musumeci G, et al. M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures. Sci Rep. 2017 Feb 1;7:41018. [3]. Wahl A, et al. Predicting HIV Pre-exposure Prophylaxis Efficacy for Women using a Preclinical Pharmacokinetic-Pharmacodynamic In Vivo Model. Sci Rep. 2017 Feb 1;7:41098. [4]. Menne S, Cote PJ, Korba BE, Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection. Antimicrob Agents Chemother. 2005 Jul;49(7):2720-8.

Frequently Asked Questions

What is the CAS number of Tenofovir disoproxil?

The CAS number of Tenofovir disoproxil is 201341-05-1.

What are the molecular formula and molecular weight of Tenofovir disoproxil?

Tenofovir disoproxil has molecular formula C19H30N5O10P and molecular weight 519.443 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tenofovir disoproxil (CAS 201341-05-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1986854-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.