Tezacaftor
Also known as: VX-661, VX 661, VX661, 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide, (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide, Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-, tezacaftorum
Tezacaftor (CAS 1152311-62-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C26H27F3N2O6 and a molecular weight of 520.498 g/mol. Key properties include a boiling point of 610.8±55.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 323.2±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1152311-62-0
- Jingsj CID
- J-1986629-6
- Molecular Formula
- C26H27F3N2O6
- Molecular Weight
- 520.498 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 610.8±55.0 °C at 760 mmHg |
|---|---|
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 323.2±31.5 °C |
| Exact Mass | 520.182129 |
| PSA | 113.18000 |
| LogP | 2.65 |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.628 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Additional Information | [1]. Treatment with VX-661 and Ivacaftor in a Phase 2 Study Resulted in Statistically Significant Improvements in Lung Function in People with Cystic Fibrosis Who Have Two Copies of the F508del Mutation. April 18, 2013 |
|---|
Frequently Asked Questions
What is the CAS number of Tezacaftor?
The CAS number of Tezacaftor is 1152311-62-0.
What are the molecular formula and molecular weight of Tezacaftor?
Tezacaftor has molecular formula C26H27F3N2O6 and molecular weight 520.498 g/mol.
What are the upstream and downstream products of Tezacaftor?
For Tezacaftor, Upstream Products: 3-Fluoro-4-nitroaniline, 5-Bromo-2,2-difluorobenzodioxole, 2,2-Difluoro-1,3-benzodioxole-5-carboxylic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Tezacaftor (CAS 1152311-62-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1986629-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.