Droloxifene

Also known as: 3-Hydroxytamoxifen, (E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol, 3-[(1E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol, (E)-1-[4'-(2-Dimethylaminoethoxy)phenyl]-1-(3-hydroxyphenyl)-2-phenylbut-1-ene, (E)-α-[p-[2-(Dimethylamino)ethoxy]phenyl]-β-ethylstilben-3-ol, E-Droloxifene, Droloxifeno, Droloxifenum, FK-435, K 060, K 060E, MFCD00468089

Droloxifene (CAS 82413-20-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C26H29NO2 and a molecular weight of 387.52300 g/mol. Key properties include a melting point of 127-129ºC, a boiling point of 526.6ºC at 760 mmHg and a density of 1.092 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.: 82413-20-5
Jingsj CID: J-1986615-0
Molecular Formula: C₂₆H₂₉NO₂
Molecular Weight: 387.52300 g/mol
Category: Organic Compounds
Last updated: 11/2/2026

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Physicochemical Properties

Melting Point	127-129ºC
Boiling Point	526.6ºC at 760 mmHg
Density	1.092 g/cm3
Exact Mass	579.24700
PSA	164.83000
LogP	4.45320
Refractive Index	1.596
Storage Conditions	Amber Vial, -20°C Freezer

Activity & Biological Data

Additional Information	[1]. Herrington DM, et al. Cardiovascular effects of droloxifene, a new selective estrogen receptor modulator, in healthypostmenopausal women. Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1606-12. [2]. Grasser WA, et al. Common mechanism for the estrogen agonist and antagonist activities of droloxifene. J Cell Biochem. 1997 May;65(2):159-71. [3]. Ke HZ, et al. Droloxifene, a new estrogen antagonist/agonist, prevents bone loss in ovariectomized rats. ndocrinology. 1995 Jun;136(6):2435-41. [4]. Huang Y, et al. Anti-implantation effect of droloxifene in rats and its relationship with anti-estrogenic activity. Acta Pharmacol Sin. 2005 Oct;26(10):1243-7.

Additional Information

[1]. Herrington DM, et al. Cardiovascular effects of droloxifene, a new selective estrogen receptor modulator, in healthypostmenopausal women. Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1606-12. [2]. Grasser WA, et al. Common mechanism for the estrogen agonist and antagonist activities of droloxifene. J Cell Biochem. 1997 May;65(2):159-71. [3]. Ke HZ, et al. Droloxifene, a new estrogen antagonist/agonist, prevents bone loss in ovariectomized rats. ndocrinology. 1995 Jun;136(6):2435-41. [4]. Huang Y, et al. Anti-implantation effect of droloxifene in rats and its relationship with anti-estrogenic activity. Acta Pharmacol Sin. 2005 Oct;26(10):1243-7.

Frequently Asked Questions

What is the CAS number of Droloxifene?

The CAS number of Droloxifene is 82413-20-5.

What are the molecular formula and molecular weight of Droloxifene?

Droloxifene has molecular formula C26H29NO2 and molecular weight 387.52300 g/mol.

What are the upstream and downstream products of Droloxifene?

For Droloxifene, Upstream Products: Anisole, 2-(3-Bromophenoxy)tetrahydro-2H-pyran, 3,4'-Dimethoxybenzophenone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 11/2/2026

How to cite: Jingsj. "Droloxifene (CAS 82413-20-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1986615-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.