Bedaquiline

Also known as: Bedaquiline (TMC-207), Sirturo, TMC207, R 207910, (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol, 3-Quinolineethanol, 6-bromo-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-, (alphaS,betaR)-

Bedaquiline (CAS 843663-66-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C32H31BrN2O2 and a molecular weight of 555.50 g/mol. Key properties include a boiling point of 702.7±60.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 378.8±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 843663-66-1
Jingsj CID: J-1986230-7
Molecular Formula: C₃₂H₃₁BrN₂O₂
Molecular Weight: 555.50 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	702.7±60.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	378.8±32.9 °C
PSA	36.36000
LogP	7.59
Vapor Pressure	0.0±2.3 mmHg at 25°C
Refractive Index	1.666
Storage Conditions	-20℃

Activity & Biological Data

Target	mycobacterial ATP synthase[1]
Additional Information	[1]. Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Apr 20. [2]. Pang Y, et al. In Vitro Activity of Bedaquiline against Nontuberculous Mycobacteria in China. Antimicrob Agents Chemother. 2017 Apr 24;61(5). [3]. Chahine EB, et al. Bedaquiline: a novel diarylquinoline for multidrug-resistant tuberculosis. Ann Pharmacother. 2014 Jan;48(1):107-15.

Target

mycobacterial ATP synthase[1]

Additional Information

[1]. Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Apr 20. [2]. Pang Y, et al. In Vitro Activity of Bedaquiline against Nontuberculous Mycobacteria in China. Antimicrob Agents Chemother. 2017 Apr 24;61(5). [3]. Chahine EB, et al. Bedaquiline: a novel diarylquinoline for multidrug-resistant tuberculosis. Ann Pharmacother. 2014 Jan;48(1):107-15.

Frequently Asked Questions

What is the CAS number of Bedaquiline?

The CAS number of Bedaquiline is 843663-66-1.

What are the molecular formula and molecular weight of Bedaquiline?

Bedaquiline has molecular formula C32H31BrN2O2 and molecular weight 555.50 g/mol.

What are the upstream and downstream products of Bedaquiline?

For Bedaquiline, Upstream Products: Dimethylamine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Bedaquiline (CAS 843663-66-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1986230-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.