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1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride

Also known as: 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanone hydrochloride, 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanone HCl, 1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride, Antitrypanosomal agent 1

1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride (CAS 75144-12-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C11H14Cl3NO and a molecular weight of 282.59400 g/mol. Key properties include a boiling point of 341.9ºC at 760 mmHg, a density of 1.22g/cm3 and a flash point of 160.6ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
75144-12-6
Jingsj CID
J-1985156-0
Molecular Formula
C11H14Cl3NO
Molecular Weight
282.59400 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point341.9ºC at 760 mmHg
Density1.22g/cm3
Flash Point160.6ºC
Exact Mass281.01400
PSA20.31000
LogP3.92980
Refractive Index1.544
Storage Conditions2-8℃

Activity & Biological Data

TargetIC50: 3.3 μM (trypanothione reductase) and 64.8 μM (glutathione reductase)[1] EC50: 1 μM (T. brucei)[1]
Additional Information[1]. Martyn DC, et al. High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1280-3.

Frequently Asked Questions

What is the CAS number of 1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride?

The CAS number of 1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride is 75144-12-6.

What are the molecular formula and molecular weight of 1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride?

1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride has molecular formula C11H14Cl3NO and molecular weight 282.59400 g/mol.

What are the upstream and downstream products of 1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride?

For 1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride, Upstream Products: 3-chloro-1-(3,4-dichlorophenyl)propan-1-one, Dimethylamine, Formaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride (CAS 75144-12-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1985156-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.