(Z)-Ligustilide

Also known as: Ligustilide, cis-Ligustilide, Ligustilide A, (3Z)-3-Butylidene-4,5-dihydro-1(3H)-isobenzofuranone, (3Z)-3-Butylidene-4,5-dihydro-2-benzofuran-1(3H)-one, 1(3H)-Isobenzofuranone, 3-butylidene-4,5-dihydro-, (3Z)-

(Z)-Ligustilide (CAS 81944-09-4) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C12H14O2 and a molecular weight of 190.238 g/mol. Key properties include a melting point of 168～169℃, a boiling point of 377.9±11.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 158.6±16.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 81944-09-4
Jingsj CID: J-1983680-5
Molecular Formula: C₁₂H₁₄O₂
Molecular Weight: 190.238 g/mol
Category: Esters
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	168～169℃
Boiling Point	377.9±11.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	158.6±16.7 °C
Exact Mass	190.099380
PSA	26.30000
LogP	2.63
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.545
Storage Conditions	2~8°C

Activity & Biological Data

Additional Information	[1]. Rodrigues AMS, et al. The antifungal potential of (Z)-ligustilide and the protective effect of eugenol demonstrated by a chemometric approach. Sci Rep. 2019 Jun 19;9(1):8729. doi: 10.1038/s41598-019-45222-y [2]. Ma H, et al. Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa. Oncotarget. 2017 Apr 25;8(17):29328-29345.

Additional Information

[1]. Rodrigues AMS, et al. The antifungal potential of (Z)-ligustilide and the protective effect of eugenol demonstrated by a chemometric approach. Sci Rep. 2019 Jun 19;9(1):8729. doi: 10.1038/s41598-019-45222-y [2]. Ma H, et al. Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa. Oncotarget. 2017 Apr 25;8(17):29328-29345.

Frequently Asked Questions

What is the CAS number of (Z)-Ligustilide?

The CAS number of (Z)-Ligustilide is 81944-09-4.

What are the molecular formula and molecular weight of (Z)-Ligustilide?

(Z)-Ligustilide has molecular formula C12H14O2 and molecular weight 190.238 g/mol.

What are the upstream and downstream products of (Z)-Ligustilide?

For (Z)-Ligustilide, Downstream Products: Levistilide A.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "(Z)-Ligustilide (CAS 81944-09-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1983680-5 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.