Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate

Also known as: 4-Pyrimidinecarboxylic acid, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-, methyl ester, Methyl 5-hydroxy-4-oxo-2-thiophen-2-yl-1H-pyrimidine-6-carboxylate, 5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acid methyl ester, Methyl 5,6-dihydroxy-2-thien-2-ylpyrimidine-4-carboxylate, Methyl 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-4-pyrimidinecarboxylate, methyl 2-(2-thienyl)-4,5-dihydroxypyrimidine-6-carboxylate, pUL89 Endonuclease-IN-1, 4-Pyrimidinecarboxylic acid,5,6-dihydroxy-2-(2-thienyl)-,methyl ester

Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate (CAS 391680-92-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C10H8N2O4S and a molecular weight of 252.24700 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 391680-92-5
Jingsj CID: J-1983385-3
Molecular Formula: C₁₀H₈N₂O₄S
Molecular Weight: 252.24700 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	252.02000
PSA	120.52000
LogP	0.99060

Activity & Biological Data

Target	IC50:0.88μM (pUL89-C)
Additional Information	[1]. Tianyu He, et al. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. J Med Chem. 2022 Apr 14;65(7):5830-5849. [2]. ianyu He, et al. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. J Med Chem. 2022 Apr 14;65(7):5830-5849.

Target

IC50:0.88μM (pUL89-C)

Additional Information

[1]. Tianyu He, et al. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. J Med Chem. 2022 Apr 14;65(7):5830-5849. [2]. ianyu He, et al. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. J Med Chem. 2022 Apr 14;65(7):5830-5849.

Frequently Asked Questions

What is the CAS number of Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate?

The CAS number of Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate is 391680-92-5.

What are the molecular formula and molecular weight of Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate?

Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate has molecular formula C10H8N2O4S and molecular weight 252.24700 g/mol.

What are the upstream and downstream products of Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate?

For Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate, Upstream Products: 2-Thiophenecarbonitrile, N'-hydroxy-2-thiophenecarboximidamide, Dimethyl acetylenedicarboxylate; Downstream Products: 5,6-dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Methyl 5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylate (CAS 391680-92-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1983385-3 (accessed 2026-11-09).

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