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(8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one

Also known as: BMN-673 (8R,9S), BMN 673 (8R,9S), BMN673 (8R,9S), (8R,9S)-BMN-673, CS-1223, (8R,9S)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one, 3H-Pyrido[4,3,2-de]phthalazin-3-one, 5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-, (8R,9S)-

(8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one (CAS 1207456-00-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C19H14F2N6O and a molecular weight of 380.35100 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
1207456-00-5
Jingsj CID
J-1983018-3
Molecular Formula
C19H14F2N6O
Molecular Weight
380.35100 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Exact Mass380.12000
PSA91.98000
LogP1.89830

Activity & Biological Data

TargetPARP-1:144 nM (IC50)
Additional Information[1]. Wang B, et al. Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-

Frequently Asked Questions

What is the CAS number of (8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one?

The CAS number of (8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one is 1207456-00-5.

What are the molecular formula and molecular weight of (8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one?

(8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one has molecular formula C19H14F2N6O and molecular weight 380.35100 g/mol.

What are the upstream and downstream products of (8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one?

For (8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one, Upstream Products: Talazoparib, 6-Fluoro-4-nitro-3H-isobenzofuran-1-one, 4-Fluorobenzaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "(8R,9S)-5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one (CAS 1207456-00-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1983018-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.