N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
Also known as: GDC-0349, GDC0349, RG-7603, 1-Ethyl-3-(4-{4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl}phenyl)urea, 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea, CS-695
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea (CAS 1207360-89-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C24H32N6O3 and a molecular weight of 452.549 g/mol. Key properties include a boiling point of 571.3±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 299.3±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1207360-89-1
- Jingsj CID
- J-1983016-1
- Molecular Formula
- C24H32N6O3
- Molecular Weight
- 452.549 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 571.3±50.0 °C at 760 mmHg |
|---|---|
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 299.3±30.1 °C |
| Exact Mass | 452.253601 |
| PSA | 95.34000 |
| LogP | 1.04 |
| Vapor Pressure | 0.0±1.6 mmHg at 25°C |
| Refractive Index | 1.620 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Target | mTOR:3.8 nM (Ki) mTORC1 mTORC2 Autophagy |
|---|---|
| Additional Information | [1]. Pei Z, et al. Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349. ACS Med Chem Lett. 2012 Nov 29;4(1):103-7. |
Frequently Asked Questions
What is the CAS number of N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea?
The CAS number of N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea is 1207360-89-1.
What are the molecular formula and molecular weight of N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea?
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea has molecular formula C24H32N6O3 and molecular weight 452.549 g/mol.
What are the upstream and downstream products of N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea?
For N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea, Upstream Products: 3-Oxetanone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea (CAS 1207360-89-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1983016-1 (accessed 2026-11-09).
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