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N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

Also known as: GDC-0349, GDC0349, RG-7603, 1-Ethyl-3-(4-{4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl}phenyl)urea, 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea, CS-695

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea (CAS 1207360-89-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C24H32N6O3 and a molecular weight of 452.549 g/mol. Key properties include a boiling point of 571.3±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 299.3±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
1207360-89-1
Jingsj CID
J-1983016-1
Molecular Formula
C24H32N6O3
Molecular Weight
452.549 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point571.3±50.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point299.3±30.1 °C
Exact Mass452.253601
PSA95.34000
LogP1.04
Vapor Pressure0.0±1.6 mmHg at 25°C
Refractive Index1.620
Storage Conditions-20℃

Activity & Biological Data

TargetmTOR:3.8 nM (Ki) mTORC1 mTORC2 Autophagy
Additional Information[1]. Pei Z, et al. Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349. ACS Med Chem Lett. 2012 Nov 29;4(1):103-7.

Frequently Asked Questions

What is the CAS number of N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea?

The CAS number of N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea is 1207360-89-1.

What are the molecular formula and molecular weight of N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea?

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea has molecular formula C24H32N6O3 and molecular weight 452.549 g/mol.

What are the upstream and downstream products of N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea?

For N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea, Upstream Products: 3-Oxetanone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea (CAS 1207360-89-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1983016-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.