Iodoacetic acid N-hydroxysuccinimide ester
Also known as: SIA Crosslinker, N-Succinimidyl iodoacetate, Succinimidyl iodoacetate, N-Hydroxysuccinimidyl iodoacetate, NHS iodoacetate, SIA, Iodoacetic acid N-succinimidyl ester, (2,5-dioxopyrrolidin-1-yl) 2-iodoacetate, 1-(2-Iodoacetoxy)-2,5-pyrrolidinedione, 2,5-Pyrrolidinedione, 1-[(2-iodoacetyl)oxy]-, N-(Iodoacetoxy)succinimide
Iodoacetic acid N-hydroxysuccinimide ester (CAS 39028-27-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C6H6INO4 and a molecular weight of 283.021 g/mol. Key properties include a melting point of 148ºC, a boiling point of 315.6±44.0 °C at 760 mmHg, a density of 2.1±0.1 g/cm3 and a flash point of 144.7±28.4 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 39028-27-8
- Jingsj CID
- J-1982902-8
- Molecular Formula
- C6H6INO4
- Molecular Weight
- 283.021 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 148ºC |
|---|---|
| Boiling Point | 315.6±44.0 °C at 760 mmHg |
| Density | 2.1±0.1 g/cm3 |
| Flash Point | 144.7±28.4 °C |
| Exact Mass | 282.934143 |
| PSA | 63.68000 |
| LogP | -0.76 |
| Vapor Pressure | 0.0±0.7 mmHg at 25°C |
| Refractive Index | 1.615 |
| Storage Conditions | −20°C |
| Additional Property | DMF: 50 mg/mL |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Non-cleavable |
|---|---|
| Additional Information | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |
Customs & Trade Information
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Iodoacetic acid N-hydroxysuccinimide ester?
The CAS number of Iodoacetic acid N-hydroxysuccinimide ester is 39028-27-8.
What are the molecular formula and molecular weight of Iodoacetic acid N-hydroxysuccinimide ester?
Iodoacetic acid N-hydroxysuccinimide ester has molecular formula C6H6INO4 and molecular weight 283.021 g/mol.
Is Iodoacetic acid N-hydroxysuccinimide ester hazardous?
Iodoacetic acid N-hydroxysuccinimide ester has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Iodoacetic acid N-hydroxysuccinimide ester?
For Iodoacetic acid N-hydroxysuccinimide ester, Upstream Products: N-Hydroxysuccinimide, iodoacetic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Iodoacetic acid N-hydroxysuccinimide ester (CAS 39028-27-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1982902-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.