Talazoparib

Also known as: BMN 673, BMN-673, BMN673, LT-673, LT-673, MDV3800, (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazine-3-one

Talazoparib (CAS 1207456-01-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H14F2N6O and a molecular weight of 380.351 g/mol. Key property: a density of 1.6±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1207456-01-6
Jingsj CID: J-1982603-0
Molecular Formula: C₁₉H₁₄F₂N₆O
Molecular Weight: 380.351 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.6±0.1 g/cm3
Exact Mass	380.119720
PSA	88.75000
LogP	1.91
Refractive Index	1.775

Activity & Biological Data

Target	PARP2:0.87 nM (Ki) PARP1:1.2 nM (Ki)
Additional Information	[1]. Wang B, et al. Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP- [2]. Shen Y, et al. BMN 673, a novel and highly potent PARP1/2 inhibitor for the treatment of human cancers with DNA repair deficiency.Clin Cancer Res. 2013 Sep 15;19(18):5003-15.

Target

PARP2:0.87 nM (Ki) PARP1:1.2 nM (Ki)

Additional Information

[1]. Wang B, et al. Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP- [2]. Shen Y, et al. BMN 673, a novel and highly potent PARP1/2 inhibitor for the treatment of human cancers with DNA repair deficiency.Clin Cancer Res. 2013 Sep 15;19(18):5003-15.

Frequently Asked Questions

What is the CAS number of Talazoparib?

The CAS number of Talazoparib is 1207456-01-6.

What are the molecular formula and molecular weight of Talazoparib?

Talazoparib has molecular formula C19H14F2N6O and molecular weight 380.351 g/mol.

What are the upstream and downstream products of Talazoparib?

For Talazoparib, Upstream Products: Talazoparib, 6-Fluoro-4-nitro-3H-isobenzofuran-1-one, 4-Fluorobenzaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Talazoparib (CAS 1207456-01-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1982603-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.