PHT-427
Also known as: 4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide, 4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide, Akt Inhibitor XIV, CS-0223, CS-303, PHT 427, PHT427
PHT-427 (CAS 1191951-57-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C20H31N3O2S2 and a molecular weight of 409.609 g/mol. Key properties include a boiling point of 535.0±43.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 277.4±28.2 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1191951-57-1
- Jingsj CID
- J-1982343-9
- Molecular Formula
- C20H31N3O2S2
- Molecular Weight
- 409.609 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 535.0±43.0 °C at 760 mmHg |
|---|---|
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 277.4±28.2 °C |
| Exact Mass | 409.185760 |
| PSA | 108.57000 |
| LogP | 7.37 |
| Vapor Pressure | 0.0±1.4 mmHg at 25°C |
| Refractive Index | 1.556 |
| Storage Conditions | -20°C |
Activity & Biological Data
| Target | Akt:2.7 μM (Ki) PDPK1:5.2 μM (Ki) |
|---|---|
| Additional Information | [1]. Meuillet EJ, et al. Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9(3):706-17. |
Frequently Asked Questions
What is the CAS number of PHT-427?
The CAS number of PHT-427 is 1191951-57-1.
What are the molecular formula and molecular weight of PHT-427?
PHT-427 has molecular formula C20H31N3O2S2 and molecular weight 409.609 g/mol.
What are the upstream and downstream products of PHT-427?
For PHT-427, Upstream Products: 2-Amino-1,3,4-thiadiazole, 4-dodecylbenzenesulfonyl chloride.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "PHT-427 (CAS 1191951-57-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1982343-9 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.