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Cephalothin

Also known as: Cefalotin, Cefalothin, Cephalotin, (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-[(Acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cephalothin (CAS 153-61-7) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C16H16N2O6S2 and a molecular weight of 396.438 g/mol. Key properties include a melting point of 160-161ºC, a boiling point of 757.2±60.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 411.8±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
153-61-7
Jingsj CID
J-1981732-1
Molecular Formula
C16H16N2O6S2
Molecular Weight
396.438 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point160-161ºC
Boiling Point757.2±60.0 °C at 760 mmHg
Density1.6±0.1 g/cm3
Flash Point411.8±32.9 °C
Exact Mass396.044983
PSA166.55000
LogP1.45
Vapor Pressure0.0±2.7 mmHg at 25°C
Refractive Index1.676
Additional Property158 MG/L

Activity & Biological Data

TargetKi: 0.32 μM (β-lactamase AmpC)[1]
Additional Information[1]. Morandi S, et al. Structure-based optimization of cephalothin-analogue boronic acids as beta-lactamase inhibitors. Bioorg Med Chem. 2008 Feb 1;16(3):1195-205. Epub 2007 Nov 7.

Frequently Asked Questions

What is the CAS number of Cephalothin?

The CAS number of Cephalothin is 153-61-7.

What are the molecular formula and molecular weight of Cephalothin?

Cephalothin has molecular formula C16H16N2O6S2 and molecular weight 396.438 g/mol.

What are the upstream and downstream products of Cephalothin?

For Cephalothin, Downstream Products: Cephalothin sodium.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Cephalothin (CAS 153-61-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1981732-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.