Desethyl Chloroquine

Also known as: Deethylchloroquine, Monodesethylchloroquine, Monodeethylchloroquine, N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine, 7-Chloro-4-{[4-(ethylamino)-1-methylbutyl]amino}quinoline, Chloroquine Related Compound D, Hydroxychloroquine Impurity D, WR 29623, NSC 13254

Desethyl Chloroquine (CAS 1476-52-4) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H22ClN3 and a molecular weight of 291.81900 g/mol. Key properties include a melting point of 94-97?C, a boiling point of 451.7ºC at 760mmHg, a density of 1.138g/cm3 and a flash point of 227ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1476-52-4
Jingsj CID: J-1981652-5
Molecular Formula: C₁₆H₂₂ClN₃
Molecular Weight: 291.81900 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	94-97?C
Boiling Point	451.7ºC at 760mmHg
Density	1.138g/cm3
Flash Point	227ºC
Exact Mass	291.15000
PSA	36.95000
LogP	4.54220
Vapor Pressure	2.38E-08mmHg at 25°C
Refractive Index	1.602
Storage Conditions	-20°C Freezer

Activity & Biological Data

Additional Information	[1]. Ajayi FO, et al. Comparison of the partitioning in vitro of chloroquine and its desethyl metabolites between the erythrocytes and plasma of healthy subjects and those with falciparum malaria. Afr J Med Med Sci. 1989 Jun;18(2):95-100. [2]. Said A, et al. Chloroquine promotes IL-17 production by CD4+ T cells via p38-dependent IL-23 release by monocyte-derived Langerhans-like cells. J Immunol. 2014 Dec 15;193(12):6135-43. [3]. Vodicka P, et al. Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice. J Huntingtons Dis. 2014;3(2):159-74.

Additional Information

[1]. Ajayi FO, et al. Comparison of the partitioning in vitro of chloroquine and its desethyl metabolites between the erythrocytes and plasma of healthy subjects and those with falciparum malaria. Afr J Med Med Sci. 1989 Jun;18(2):95-100. [2]. Said A, et al. Chloroquine promotes IL-17 production by CD4+ T cells via p38-dependent IL-23 release by monocyte-derived Langerhans-like cells. J Immunol. 2014 Dec 15;193(12):6135-43. [3]. Vodicka P, et al. Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice. J Huntingtons Dis. 2014;3(2):159-74.

Customs & Trade Information

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Desethyl Chloroquine?

The CAS number of Desethyl Chloroquine is 1476-52-4.

What are the molecular formula and molecular weight of Desethyl Chloroquine?

Desethyl Chloroquine has molecular formula C16H22ClN3 and molecular weight 291.81900 g/mol.

What are the upstream and downstream products of Desethyl Chloroquine?

For Desethyl Chloroquine, Upstream Products: Ethylamine, Chloroquine, 4,7-Dichloroquinoline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Desethyl Chloroquine (CAS 1476-52-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1981652-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.