Pioglitazone hydrochloride
Also known as: Pioglitazone HCl, AD-4833, Actos, 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride, 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride, 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride, 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, hydrochloride (1:1), U-72107A, Pioglitazone (hydrochloride), JQT35NPK6C
Pioglitazone hydrochloride (CAS 112529-15-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C19H21ClN2O3S and a molecular weight of 392.900 g/mol. Key properties include a melting point of 193-194ºC, a boiling point of 575.4ºC at 760 mmHg, a density of 1.26 g/cm3 and a flash point of 301.8ºC. It is classified under GHS with signal word Warning and hazard statements H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 112529-15-4
- Jingsj CID
- J-1981489-2
- Molecular Formula
- C19H21ClN2O3S
- Molecular Weight
- 392.900 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 193-194ºC |
|---|---|
| Boiling Point | 575.4ºC at 760 mmHg |
| Density | 1.26 g/cm3 |
| Flash Point | 301.8ºC |
| Exact Mass | 392.096130 |
| PSA | 93.59000 |
| LogP | 4.29040 |
| Vapor Pressure | 0mmHg at 25°C |
| Refractive Index | 1.64 |
| Storage Conditions | Desiccate at RT |
GHS Safety & Compliance
- H319 — Causes serious eye irritation
Activity & Biological Data
| Target | PPARδ:0.01 μM (EC50, Human PPARδ) PPARα:0.93 μM (EC50, Human PPARα) PPARγ:43 μM (EC50, Human PPARγ) |
|---|---|
| Additional Information | [1]. Kuwabara K, et al. A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose leve [2]. Puddu A, et al. Pioglitazone attenuates the detrimental effects of advanced glycation end-products in the pancreatic beta cell line HIT-T15. Regul Pept. 2012 Aug 20;177(1-3):79-84. [3]. Kubota N, et al. Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways. J Biol Chem. 2006 Mar 31;281(13):8748-55. [4]. Elrashidy RA, et al. Pioglitazone attenuates cardiac fibrosis and hypertrophy in a rat model of diabetic nephropathy. J Cardiovasc Pharmacol Ther. 2012 Sep;17(3):324-33. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Pioglitazone hydrochloride?
The CAS number of Pioglitazone hydrochloride is 112529-15-4.
What are the molecular formula and molecular weight of Pioglitazone hydrochloride?
Pioglitazone hydrochloride has molecular formula C19H21ClN2O3S and molecular weight 392.900 g/mol.
Is Pioglitazone hydrochloride hazardous?
Pioglitazone hydrochloride has GHS signal word Warning and hazard statements H319 — Causes serious eye irritation.
What are the upstream and downstream products of Pioglitazone hydrochloride?
For Pioglitazone hydrochloride, Upstream Products: Pioglitazone hydrochloride, 2-Amino-5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl]thiazol-4(5H)-one, 5-Ethyl-2-pyridineethanol; Downstream Products: Pioglitazone N-Oxide.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Pioglitazone hydrochloride (CAS 112529-15-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1981489-2 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.