Skip to main content

Epothilone A

Also known as: (-)-Epothilone A, Epo A, Epothilon A, Epothilone-S, UNII-51E07YBX96, Ixabepilone Impurity 5 (Epothilone A), (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione, (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

Epothilone A (CAS 152044-53-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C26H39NO6S and a molecular weight of 493.656 g/mol. Key properties include a melting point of 95ºC, a boiling point of 683.3±55.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 367.1±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
152044-53-6
Jingsj CID
J-1980457-0
Molecular Formula
C26H39NO6S
Molecular Weight
493.656 g/mol
Category
Organic Compounds
Last updated
8/21/2026

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point95ºC
Boiling Point683.3±55.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point367.1±31.5 °C
Exact Mass493.249817
PSA137.49000
LogP2.54
Vapor Pressure0.0±2.2 mmHg at 25°C
Refractive Index1.532
Storage Conditions-20°C

Activity & Biological Data

Additional Information[1]. Kowalski RJ, et al. Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)). J Biol Chem. 1997 Jan 24;272(4):2534-41. [2]. Cheng KL, et al. Novel microtubule-targeting agents - the epothilones. Biologics. 2008 Dec;2(4):789-811.

Frequently Asked Questions

What is the CAS number of Epothilone A?

The CAS number of Epothilone A is 152044-53-6.

What are the molecular formula and molecular weight of Epothilone A?

Epothilone A has molecular formula C26H39NO6S and molecular weight 493.656 g/mol.

What are the upstream and downstream products of Epothilone A?

For Epothilone A, Upstream Products: Epothilone C, 2-Methyl-1,3-thiazole-4-carbaldehyde, Ethyl 2-methylthiazole-4-carboxylate; Downstream Products: Epothilone C.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Epothilone A (CAS 152044-53-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1980457-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.