β-Lapachone

Also known as: 3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione, 2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione, ARQ-501, NSC-26326, SL-11001, CO-501, beta-Lapachone, b-Lapachone

β-Lapachone (CAS 4707-32-8) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C15H14O3 and a molecular weight of 242.270 g/mol. Key properties include a melting point of >110ºC (dec.), a boiling point of 381.4±42.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 169.7±27.9 °C. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.: 4707-32-8
Jingsj CID: J-1980387-3
Molecular Formula: C₁₅H₁₄O₃
Molecular Weight: 242.270 g/mol
Category: Ketones
Last updated: 11/3/2026

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Physicochemical Properties

Melting Point	>110ºC (dec.)
Boiling Point	381.4±42.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	169.7±27.9 °C
Exact Mass	242.094299
PSA	43.37000
LogP	2.82
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.595
Storage Conditions	-20?C Freezer

Activity & Biological Data

Target	Topoisomerase I
Additional Information	[1]. Li CJ, et al. beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin. J Biol Chem. 1993 Oct 25;268(30):22463-8. [2]. Vanni A, et al. DNA damage and cytotoxicity induced by beta-lapachone: relation to poly(ADP-ribose) polymerase inhibition. Mutat Res. 1998 Jun 5;401(1-2):55-63. [3]. Kim TW, et al. β-Lapachone enhances Mre11-Rad50-Nbs1 complex expression in cisplatin-induced nephrotoxicity. Pharmacol Rep. 2016 Feb;68(1):27-31.

Target

Topoisomerase I

Additional Information

[1]. Li CJ, et al. beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin. J Biol Chem. 1993 Oct 25;268(30):22463-8. [2]. Vanni A, et al. DNA damage and cytotoxicity induced by beta-lapachone: relation to poly(ADP-ribose) polymerase inhibition. Mutat Res. 1998 Jun 5;401(1-2):55-63. [3]. Kim TW, et al. β-Lapachone enhances Mre11-Rad50-Nbs1 complex expression in cisplatin-induced nephrotoxicity. Pharmacol Rep. 2016 Feb;68(1):27-31.

Customs & Trade Information

HS Code	2914399090
Summary	2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of β-Lapachone?

The CAS number of β-Lapachone is 4707-32-8.

What are the molecular formula and molecular weight of β-Lapachone?

β-Lapachone has molecular formula C15H14O3 and molecular weight 242.270 g/mol.

What are the upstream and downstream products of β-Lapachone?

For β-Lapachone, Upstream Products: Lapachol, Dihydrolapachenol, Formaldehyde; Downstream Products: 5-hydroxyisobenzofuran-1,3-dione, Phthalic acid, 2,2-Dimethyl-3,4-dihydro-2H-benzo[h]chromene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 11/3/2026

How to cite: Jingsj. "β-Lapachone (CAS 4707-32-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1980387-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.