Doxercalciferol

Also known as: 1α-Hydroxyvitamin D2, 1α-Hydroxyergocalciferol, 1-Hydroxyergocalciferol, 1-Hydroxyvitamin D2, 1-alpha-hydroxyergocalciferol, 1-alpha-hydroxyvitamin D2, 1ALPHA-OH-D2, Hectorol, Ercalcidol, UNII-3DIZ9LF5Y9, (1R,3S,5Z)-4-methylidene-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethylhex-2-en-1-yl]octahydro-4H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol, (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol, 9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol, (1α,3β,5Z,7E,22E,24R)-

Doxercalciferol (CAS 54573-75-0) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C28H44O2 and a molecular weight of 412.648 g/mol. Key properties include a melting point of 138-140ºC, a boiling point of 538.7±50.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 224.0±24.7 °C. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 54573-75-0
Jingsj CID: J-1979993-0
Molecular Formula: C₂₈H₄₄O₂
Molecular Weight: 412.648 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	138-140ºC
Boiling Point	538.7±50.0 °C at 760 mmHg
Density	1.0±0.1 g/cm3
Flash Point	224.0±24.7 °C
Exact Mass	412.334137
PSA	40.46000
LogP	8.15
Vapor Pressure	0.0±3.3 mmHg at 25°C
Refractive Index	1.541
Storage Conditions	Desiccate at -20°C

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H300

Activity & Biological Data

Target	Vitamin D receptor[1]
Additional Information	[1]. Noonan W, et al. Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol Dial Transplant. 2008 Dec;23(12):3824-30. [2]. Wang XX, et al. Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism. Am J Physiol Renal Physiol. 2011 Mar;300(3):F801-10. [3]. Wang Y, et al. Vitamin D receptor signaling in podocytes protects against diabetic nephropathy. J Am Soc Nephrol. 2012 Dec;23(12):1977-86.

Target

Vitamin D receptor[1]

Additional Information

[1]. Noonan W, et al. Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol Dial Transplant. 2008 Dec;23(12):3824-30. [2]. Wang XX, et al. Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism. Am J Physiol Renal Physiol. 2011 Mar;300(3):F801-10. [3]. Wang Y, et al. Vitamin D receptor signaling in podocytes protects against diabetic nephropathy. J Am Soc Nephrol. 2012 Dec;23(12):1977-86.

Frequently Asked Questions

What is the CAS number of Doxercalciferol?

The CAS number of Doxercalciferol is 54573-75-0.

What are the molecular formula and molecular weight of Doxercalciferol?

Doxercalciferol has molecular formula C28H44O2 and molecular weight 412.648 g/mol.

Is Doxercalciferol hazardous?

Doxercalciferol has GHS signal word Danger and hazard statements H300.

What are the upstream and downstream products of Doxercalciferol?

For Doxercalciferol, Upstream Products: Ergocalciferol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Doxercalciferol (CAS 54573-75-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1979993-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.