Ivabradine hydrochloride

Also known as: Ivabradine HCl, Procoralan, Corlanor, Corlentor, S-16257, 3-[3-[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride, 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride, MFCD00929899, UNII-TP19837BZK

Ivabradine hydrochloride (CAS 148849-67-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C27H37ClN2O5 and a molecular weight of 505.046 g/mol. Key properties include a melting point of 193-196?C, a boiling point of 626.9ºC at 760mmHg and a flash point of 332.9ºC. It is classified under GHS with signal word Warning and hazard statements H400 — Very toxic to aquatic life. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 148849-67-6
Jingsj CID: J-1979807-3
Molecular Formula: C₂₇H₃₇ClN₂O₅
Molecular Weight: 505.046 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	193-196?C
Boiling Point	626.9ºC at 760mmHg
Flash Point	332.9ºC
Exact Mass	504.239105
PSA	60.47000
LogP	4.04990
Vapor Pressure	1.24E-15mmHg at 25°C
Storage Conditions	-20°C Freezer

GHS Safety & Compliance

Environmental HazardSignal word: Warning

H400 — Very toxic to aquatic life

Activity & Biological Data

Additional Information	[1]. Fang, Y., et al. Heart rate reduction induced by the if current inhibitor ivabradine improves diastolic function and attenuates cardiac tissue hypoxia. J Cardiovasc Pharmacol, 2012. 59(3): p. 260-7. [2]. Kroller-Schon, S., et al. Differential effects of heart rate reduction with ivabradine in two models of endothelial dysfunction and oxidative stress. Basic Res Cardiol, 2011. 106(6): p. 1147-58.

Additional Information

[1]. Fang, Y., et al. Heart rate reduction induced by the if current inhibitor ivabradine improves diastolic function and attenuates cardiac tissue hypoxia. J Cardiovasc Pharmacol, 2012. 59(3): p. 260-7. [2]. Kroller-Schon, S., et al. Differential effects of heart rate reduction with ivabradine in two models of endothelial dysfunction and oxidative stress. Basic Res Cardiol, 2011. 106(6): p. 1147-58.

Frequently Asked Questions

What is the CAS number of Ivabradine hydrochloride?

The CAS number of Ivabradine hydrochloride is 148849-67-6.

What are the molecular formula and molecular weight of Ivabradine hydrochloride?

Ivabradine hydrochloride has molecular formula C27H37ClN2O5 and molecular weight 505.046 g/mol.

Is Ivabradine hydrochloride hazardous?

Ivabradine hydrochloride has GHS signal word Warning and hazard statements H400 — Very toxic to aquatic life.

What are the upstream and downstream products of Ivabradine hydrochloride?

For Ivabradine hydrochloride, Upstream Products: Ivabradine, 7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one, 4,5-Dimethoxy-1-cyanobenzocyclobutane; Downstream Products: Ivabradine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ivabradine hydrochloride (CAS 148849-67-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1979807-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.