Migalastat hydrochloride

Also known as: 1-Deoxygalactonojirimycin hydrochloride, DGJ hydrochloride, Galactostatin hydrochloride, GR181413A, 1,5-Dideoxy-1,5-imino-D-galactitol hydrochloride, Migalastat HCl, UNII-CLY7M0XD20, Deoxygalactonojirimycin hydrochloride

Migalastat hydrochloride (CAS 75172-81-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C6H14ClNO4 and a molecular weight of 199.63 g/mol. Key properties include a melting point of 260ºC, a boiling point of 382.7ºC at 760 mmHg and a flash point of 185.2ºC. It is listed by 1 supplier, from 26.40 to 39.60 CNY. Record last updated Aug 21, 2026.

CAS No.: 75172-81-5
Jingsj CID: J-1978229-8
Molecular Formula: C₆H₁₄ClNO₄
Molecular Weight: 199.63 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Supplier	Purity / Pack	Base Price	Unit Price	Origin
Maikuo Made to Order	98% 250mg	¥6,600.00	$3.95 /mgBest ¥26.40/mg CNY	CN China MOQ 250mg	View Product
Maikuo Made to Order	98% 100mg	¥3,600.00	$5.39 /mg ¥36.00/mg CNY	CN China MOQ 100mg	View Product
Maikuo Made to Order	98% 50mg	¥1,980.00	$5.93 /mg ¥39.60/mg CNY	CN China MOQ 50mg	View Product

Physicochemical Properties

Melting Point	260ºC
Boiling Point	382.7ºC at 760 mmHg
Flash Point	185.2ºC
Exact Mass	199.06100
PSA	92.95000
SMILES	C1[C@@H]([C@H]([C@H]([C@H](N1)CO)O)O)O.Cl
InChIKey	ZJIHMALTJRDNQI-OLALXQGDSA-N
InChI	1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5+,6-;/m1./s1

Activity & Biological Data

Target	IC50: 0.04 μM (human α-Gal A)[1];Ki: 0.04 μM (human α-Gal A)[1]
Additional Information	[1]. Asano N, et al. In vitro inhibition and intracellular enhancement of lysosomal alpha-galactosidase A activity in Fabry lymphoblasts by 1-deoxygalactonojirimycin and its derivatives. Eur J Biochem. 2000 Jul;267(13):4179-86. [2]. Ishii S, et al. Preclinical efficacy and safety of 1-deoxygalactonojirimycin in mice for Fabry disease. J Pharmacol Exp Ther. 2009 Mar;328(3):723-31. [3]. Young-Gqamana B, et al. Migalastat HCl reduces globotriaosylsphingosine (lyso-Gb3) in Fabry transgenic mice and in the plasma of Fabry patients. PLoS One. 2013;8(3):e57631.

Target

IC50: 0.04 μM (human α-Gal A)[1];Ki: 0.04 μM (human α-Gal A)[1]

Additional Information

[1]. Asano N, et al. In vitro inhibition and intracellular enhancement of lysosomal alpha-galactosidase A activity in Fabry lymphoblasts by 1-deoxygalactonojirimycin and its derivatives. Eur J Biochem. 2000 Jul;267(13):4179-86. [2]. Ishii S, et al. Preclinical efficacy and safety of 1-deoxygalactonojirimycin in mice for Fabry disease. J Pharmacol Exp Ther. 2009 Mar;328(3):723-31. [3]. Young-Gqamana B, et al. Migalastat HCl reduces globotriaosylsphingosine (lyso-Gb3) in Fabry transgenic mice and in the plasma of Fabry patients. PLoS One. 2013;8(3):e57631.

Frequently Asked Questions

What is the CAS number of Migalastat hydrochloride?

The CAS number of Migalastat hydrochloride is 75172-81-5.

What are the molecular formula and molecular weight of Migalastat hydrochloride?

Migalastat hydrochloride has molecular formula C6H14ClNO4 and molecular weight 199.63 g/mol.

Which suppliers offer Migalastat hydrochloride?

1 supplier(s) listed; reference unit price ¥26.40–39.60 /mg.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Migalastat hydrochloride (CAS 75172-81-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1978229-8 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.