Kartogenin

Also known as: 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid, 2-(4-Biphenylylcarbamoyl)benzoic acid, 2-(Biphenyl-4-ylcarbamoyl)benzoic acid, 4'-Phenylphthalanilic Acid, KGN, n-Biphenyl-4-yl-phthalamic acid

Kartogenin (CAS 4727-31-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C20H15NO3 and a molecular weight of 317.338 g/mol. Key properties include a boiling point of 464.4±38.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 234.6±26.8 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H319 — Causes serious eye irritation and H410 — Very toxic to aquatic life with long lasting effects. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 4727-31-5
Jingsj CID: J-1977898-9
Molecular Formula: C₂₀H₁₅NO₃
Molecular Weight: 317.338 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	464.4±38.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	234.6±26.8 °C
Exact Mass	317.105194
PSA	66.40000
LogP	3.81
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.674
Storage Conditions	room temp
Additional Property	DMSO: >15mg/mL

GHS Safety & Compliance

Irritant / Environmental HazardSignal word: Warning

H302 — Harmful if swallowed
H319 — Causes serious eye irritation
H410 — Very toxic to aquatic life with long lasting effects

Activity & Biological Data

Additional Information	[1]. Zhang J, et al. Kartogenin induces cartilage-like tissue formation in tendon-bone junction. Bone Res. 2014;2. pii: 14008. [2]. Wang J, et al. A heterocyclic molecule kartogenin induces collagen synthesis of human dermal fibroblasts by activating the smad4/smad5 pathway. Biochem Biophys Res Commun. 2014 Jul 18;450(1):568-74. [3]. Ono Y, et al. Chondroprotective Effect of Kartogenin on CD44-Mediated Functions in Articular Cartilage and Chondrocytes. Cartilage. 2014 Jul;5(3):172-80.

Additional Information

[1]. Zhang J, et al. Kartogenin induces cartilage-like tissue formation in tendon-bone junction. Bone Res. 2014;2. pii: 14008. [2]. Wang J, et al. A heterocyclic molecule kartogenin induces collagen synthesis of human dermal fibroblasts by activating the smad4/smad5 pathway. Biochem Biophys Res Commun. 2014 Jul 18;450(1):568-74. [3]. Ono Y, et al. Chondroprotective Effect of Kartogenin on CD44-Mediated Functions in Articular Cartilage and Chondrocytes. Cartilage. 2014 Jul;5(3):172-80.

Customs & Trade Information

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Kartogenin?

The CAS number of Kartogenin is 4727-31-5.

What are the molecular formula and molecular weight of Kartogenin?

Kartogenin has molecular formula C20H15NO3 and molecular weight 317.338 g/mol.

Is Kartogenin hazardous?

Kartogenin has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H319 — Causes serious eye irritation; H410 — Very toxic to aquatic life with long lasting effects.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Kartogenin (CAS 4727-31-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1977898-9 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.