Razoxane
Also known as: ICRF 159, NSC 129943, 4,4'-(1-methyl-1,2-ethanediyl)bis[2,6-piperazinedione], 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione), 4,4'-propylenebis(piperazine-2,6-dione), 4,4'-Propane-1,2-diyldipiperazine-2,6-dione, 1,2-bis(3,5-dioxo-1-piperazinyl)propane, (±)-1,2-bis(3,5-dioxopiperazin-1-yl)propane, dl-1,2-bis(3,5-dioxopiperazin-1-yl)-propane, Razoxin, Tepirone, Troxozone, Propyliminum, RAZOXANUM, 2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis-
Razoxane (CAS 21416-67-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C11H16N4O4 and a molecular weight of 268.26900 g/mol. Key properties include a melting point of 193ºC, a boiling point of 531.5ºC at 760mmHg, a density of 1.333g/cm3 and a flash point of 275.3ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 21416-67-1
- Jingsj CID
- J-1977687-5
- Molecular Formula
- C11H16N4O4
- Molecular Weight
- 268.26900 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 193ºC |
|---|---|
| Boiling Point | 531.5ºC at 760mmHg |
| Density | 1.333g/cm3 |
| Flash Point | 275.3ºC |
| Exact Mass | 268.11700 |
| PSA | 98.82000 |
| Vapor Pressure | 1.33E-13mmHg at 25°C |
| Refractive Index | 1.534 |
| Storage Conditions | room temp |
| Additional Property | DMSO: soluble40mg/mL |
Activity & Biological Data
| Target | Topoisomerase II |
|---|---|
| Additional Information | [1]. J P Braybrooke, et al. A phase II study of Razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis. Clin Cancer Res.2000; 6(12):4697-704. [2]. F Wingen, et al. Antimetastatic effects of Razoxane in a rat osteosarcoma model. Clin Exp Metastasis.Jan-Mar 1987; 5(1):9-16. |
Frequently Asked Questions
What is the CAS number of Razoxane?
The CAS number of Razoxane is 21416-67-1.
What are the molecular formula and molecular weight of Razoxane?
Razoxane has molecular formula C11H16N4O4 and molecular weight 268.26900 g/mol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Razoxane (CAS 21416-67-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1977687-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.