spiclomazine
Also known as: 8-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one, Clospirazine, Espiclomazina, Spiclomazine [INN], Spiclomazinum, Spiclomazinum [INN-Latin]
spiclomazine (CAS 24527-27-3) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H24ClN3OS2 and a molecular weight of 446.03 g/mol. Key properties include a boiling point of 695.3ºC at 760mmHg, a density of 1.42g/cm3 and a flash point of 374.3ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 24527-27-3
- Jingsj CID
- J-1976587-3
- Molecular Formula
- C22H24ClN3OS2
- Molecular Weight
- 446.03 g/mol
- Category
- Organohalogen Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 695.3ºC at 760mmHg |
|---|---|
| Density | 1.42g/cm3 |
| Flash Point | 374.3ºC |
| Exact Mass | 445.10500 |
| PSA | 86.18000 |
| LogP | 5.31960 |
| Vapor Pressure | 3.51E-19mmHg at 25°C |
| Refractive Index | 1.724 |
Activity & Biological Data
| Target | KRAS(G12C) |
|---|---|
| Additional Information | [1]. Guo X, et al. Spiclomazine displays a preferential anti-tumor activity in mutant KRas-driven pancreatic cancer. Oncotarget. 2018 Jan 8;9(6):6938-6951. |
Frequently Asked Questions
What is the CAS number of spiclomazine?
The CAS number of spiclomazine is 24527-27-3.
What are the molecular formula and molecular weight of spiclomazine?
spiclomazine has molecular formula C22H24ClN3OS2 and molecular weight 446.03 g/mol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "spiclomazine (CAS 24527-27-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1976587-3 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.