Promestriene

Also known as: 3-Propoxy-17β-methoxyestra-1,3,5(10)-triene, (17β)-17-Methoxy-3-propoxyestra-1,3,5(10)-triene, 17-Methoxy-3-propoxyestra-1,3,5(10)-triene, 3-Propoxy-17-methoxyestra-1,3,5(10)-triene, 3-Propoxy-17b-methoxyestra-1,3,5(10)-triene, 3-Propoxy-17beta-methoxy-1,3,5(10)-estratriene, 17-BETA-ESTRADIOL 3-PROPYL ETHER 17-METHYL ETHER, 17β-Methoxy-3-propoxyestra-1,3,5(10)-triene, Estra-1,3,5(10)-triene, 17-methoxy-3-propoxy-, Promestriene (DCF/INN)

Promestriene (CAS 39219-28-8) is a compound in the Aliphatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C22H32O2 and a molecular weight of 328.488 g/mol. Key properties include a melting point of 64-660ºC, a boiling point of 436.8±45.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 153.3±28.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 39219-28-8
Jingsj CID: J-1975815-6
Molecular Formula: C₂₂H₃₂O₂
Molecular Weight: 328.488 g/mol
Category: Aliphatic Hydrocarbons
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	64-660ºC
Boiling Point	436.8±45.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	153.3±28.3 °C
Exact Mass	328.240234
PSA	18.46000
LogP	6.48
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.546
Storage Conditions	-20°C Freezer

Activity & Biological Data

Additional Information	[1]. Isabel Santos, et al. Urogenital Disorders Associated With Oestrogen Deficiency: The Role of Promestriene as Topical Oestrogen Therapy. Gynecol Endocrinol. 2010 Sep;26(9):644-51. [2]. Lino Del Pup, et al. Promestriene, a Specific Topic Estrogen. Review of 40 Years of Vaginal Atrophy Treatment: Is It Safe Even in Cancer Patients. Anticancer Drugs. 2013 Nov;24(10):989-98. [3]. AJO Almodovar, et al. Abstract P5-05-07: Promestriene effects on estrogen-sensitive breast cancer cell proliferation in vitro. Cancer Res 2013;73(24 Suppl): Abstract nr P5-05-07.

Additional Information

[1]. Isabel Santos, et al. Urogenital Disorders Associated With Oestrogen Deficiency: The Role of Promestriene as Topical Oestrogen Therapy. Gynecol Endocrinol. 2010 Sep;26(9):644-51. [2]. Lino Del Pup, et al. Promestriene, a Specific Topic Estrogen. Review of 40 Years of Vaginal Atrophy Treatment: Is It Safe Even in Cancer Patients. Anticancer Drugs. 2013 Nov;24(10):989-98. [3]. AJO Almodovar, et al. Abstract P5-05-07: Promestriene effects on estrogen-sensitive breast cancer cell proliferation in vitro. Cancer Res 2013;73(24 Suppl): Abstract nr P5-05-07.

Frequently Asked Questions

What is the CAS number of Promestriene?

The CAS number of Promestriene is 39219-28-8.

What are the molecular formula and molecular weight of Promestriene?

Promestriene has molecular formula C22H32O2 and molecular weight 328.488 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Promestriene (CAS 39219-28-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975815-6 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.