Daurisoline
Also known as: Daurisoline, (R,R)-Daurisoline, O7-Demethyldauricine, aurisoline, DS, 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-hydroxy-3-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenyl]methyl]-6-methoxy-2-methyl-, (1R)-
Daurisoline (CAS 70553-76-3) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C37H42N2O6 and a molecular weight of 610.739 g/mol. Key properties include a melting point of 96-102ºC, a boiling point of 724.5±60.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 392.0±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 70553-76-3
- Jingsj CID
- J-1975676-1
- Molecular Formula
- C37H42N2O6
- Molecular Weight
- 610.739 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 96-102ºC |
|---|---|
| Boiling Point | 724.5±60.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 392.0±32.9 °C |
| Exact Mass | 610.304260 |
| PSA | 83.86000 |
| LogP | 5.84 |
| Vapor Pressure | 0.0±2.4 mmHg at 25°C |
| Refractive Index | 1.618 |
| Storage Conditions | ?20°C |
| Additional Property | DMSO: soluble15mg/mL, clear |
Activity & Biological Data
| Target | hERG[1], autophagy[2] |
|---|---|
| Additional Information | [1]. Liu Q, et al. Effect of daurisoline on HERG channel electrophysiological function and protein expression. J Nat Prod. 2012 Sep 28;75(9):1539-45. [2]. Wu MY, et al. Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells tocamptothecin-induced toxicity. Oncotarget. 2017 Sep 8;8(44):77673-77684. [3]. Shi SJ, et al. Pharmacokinetic-pharmacodynamic modeling of daurisoline and dauricine in beagle dogs. Acta Pharmacol Sin. 2003 Oct;24(10):1011-5. |
Frequently Asked Questions
What is the CAS number of Daurisoline?
The CAS number of Daurisoline is 70553-76-3.
What are the molecular formula and molecular weight of Daurisoline?
Daurisoline has molecular formula C37H42N2O6 and molecular weight 610.739 g/mol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Daurisoline (CAS 70553-76-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975676-1 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.