Indirubin

Also known as: Indirubin (NSC 105327), Indigo Red, 2-(2-oxo-1H-indol-3-ylidene)-1H-indol-3-one, Couroupitine B, C.I. 73200, Indigopurpurin, 2,3'-Biindole-2',3(1H,1'H)-dione, NSC105327, Indigo Red

Indirubin (CAS 479-41-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H10N2O2 and a molecular weight of 262.263 g/mol. Key properties include a melting point of 350 °C, a boiling point of 496.6±45.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 207.0±28.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 479-41-4
Jingsj CID: J-1975591-0
Molecular Formula: C₁₆H₁₀N₂O₂
Molecular Weight: 262.263 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	350 °C
Boiling Point	496.6±45.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	207.0±28.9 °C
Exact Mass	262.074219
PSA	58.20000
LogP	2.48
Vapor Pressure	0.0±1.3 mmHg at 25°C
Refractive Index	1.709

Activity & Biological Data

Additional Information	[1]. Kim MH, et al. Indirubin, a purple 3,2- bisindole, inhibited allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model. J Ethnopharmacol. 2013 Jan 9;145(1):214-9. [2]. Hsieh WL, et al. Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF-induced CDC25B gene expression in epidermal keratinocytes. J Dermatol Sci. 2012 Aug;67(2):140-6. [3]. Zhang X, et al. Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell. Int J Cancer. 2011 Nov 15;129(10):2502-11. [4]. Alex D, et al. Indirubin shows anti-angiogenic activity in an in vivo zebrafish model and an in vitro HUVEC model. J Ethnopharmacol. 2010 Sep 15;131(2):242-7.

Additional Information

[1]. Kim MH, et al. Indirubin, a purple 3,2- bisindole, inhibited allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model. J Ethnopharmacol. 2013 Jan 9;145(1):214-9. [2]. Hsieh WL, et al. Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF-induced CDC25B gene expression in epidermal keratinocytes. J Dermatol Sci. 2012 Aug;67(2):140-6. [3]. Zhang X, et al. Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell. Int J Cancer. 2011 Nov 15;129(10):2502-11. [4]. Alex D, et al. Indirubin shows anti-angiogenic activity in an in vivo zebrafish model and an in vitro HUVEC model. J Ethnopharmacol. 2010 Sep 15;131(2):242-7.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Indirubin?

The CAS number of Indirubin is 479-41-4.

What are the molecular formula and molecular weight of Indirubin?

Indirubin has molecular formula C16H10N2O2 and molecular weight 262.263 g/mol.

What are the upstream and downstream products of Indirubin?

For Indirubin, Upstream Products: Indoxyl acetate, isatin, Indole; Downstream Products: isatin, Indole, Indigo.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Indirubin (CAS 479-41-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975591-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.