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2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid

Also known as: SR 48692, Meclinertant, Reminertant, Merclinertant, 2-({[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)-2-adamantanecarboxylic acid, 2-({[1-(7-Chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)adamantane-2-carboxylic acid

2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid (CAS 146362-70-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C32H31ClN4O5 and a molecular weight of 587.065 g/mol. Key properties include a boiling point of 781.2±60.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 426.2±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
146362-70-1
Jingsj CID
J-1975355-0
Molecular Formula
C32H31ClN4O5
Molecular Weight
587.065 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026
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Physicochemical Properties

Boiling Point781.2±60.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point426.2±32.9 °C
Exact Mass586.198303
PSA119.06000
LogP4.55
Vapor Pressure0.0±2.8 mmHg at 25°C
Refractive Index1.729
Storage Conditions-20°C

Activity & Biological Data

TargetNeurotensin receptor 1 (NTS1)[1]
Additional Information[1]. Gully D, et al. Biochemical and pharmacological profile of a potent and selective nonpeptide antagonist of the neurotensin receptor. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):65-9. [2]. Griebel G, et al. Characterization of the profile of neurokinin-2 and neurotensin receptor antagonists in the mouse defense test battery. Neurosci Biobehav Rev. 2001 Dec;25(7-8):619-26. [3]. Felszeghy K, et al. Neurotensin receptor antagonist administered during cocaine withdrawal decreases locomotor sensitization and conditioned place preference. Neuropsychopharmacology. 2007 Dec;32(12):2601-10.

Frequently Asked Questions

What is the CAS number of 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid?

The CAS number of 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid is 146362-70-1.

What are the molecular formula and molecular weight of 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid?

2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid has molecular formula C32H31ClN4O5 and molecular weight 587.065 g/mol.

What are the upstream and downstream products of 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid?

For 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid, Upstream Products: 2',6'-Dimethoxyacetophenone, 2-Aminoadamantane-2-carboxylic acid, 2'-Hydroxy-6'-methoxyacetophenone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid (CAS 146362-70-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975355-0 (accessed 2026-11-09).

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